Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1982 Feb;35(2):167–171. doi: 10.1136/jcp.35.2.167

Lysosomal localisation of parallel tubular arrays in chronic lymphocytic leukaemia of T cell origin: an ultrastructural cytochemical study.

F Capron, J Y PErrot, C Boucheix, M Reynes, V Tricottet, A Bernadou, J Diebold
PMCID: PMC497490  PMID: 6279700

Abstract

An ultrastructural cytochemical study of lysosomal acid phosphatase was performed on leukemic cells in a case of chronic lymphocytic leukaemia of T cell origin (T-CLL). The cells showed inclusion bodies known as parallel tubular arrays, which often lay within acid phosphatase-positive, membrane-bound spaces. This suggests their lysosomal location.

Full text

PDF
167

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boucheix C., Diebold J., Bernadou A., Reynes M., Tulliez M., Cadiou M., Paczynski V., Capron F., Bilski-Pasquier G. Lymphoblastic lymphoma/leukemia with convoluted nuclei: the question of its relation to the T-cell lineage studied in 13 patients. Cancer. 1980 Apr 1;45(7):1569–1577. doi: 10.1002/1097-0142(19800401)45:7<1569::aid-cncr2820450710>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  2. Brouet J. C., Sasportes M., Flandrin G., Preud'Homme J. L., Seligmann M. Chronic lymphocytic leukaemia of T-cell origin. Immunological and clinical evaluation in eleven patients. Lancet. 1975 Nov 8;2(7941):890–893. doi: 10.1016/s0140-6736(75)92127-3. [DOI] [PubMed] [Google Scholar]
  3. Catovsky D., Pittman S., O'Brien M., Cherchi M., Costello C., Foa R., Pearce E., Hoffbrand A. V., Janossy G., Ganeshaguru K. Multiparameter studies in lymphoid leukemias. Am J Clin Pathol. 1979 Oct;72(4 Suppl):736–745. [PubMed] [Google Scholar]
  4. Goodman J. R., Sylvester R. A., Talal N., Tuffanelli D. L. Virus-like structures in lymphocytes of patients with systemic and discoid lupus erythematosus. Ann Intern Med. 1973 Sep;79(3):396–402. doi: 10.7326/0003-4819-79-3-396. [DOI] [PubMed] [Google Scholar]
  5. Hovig T., Jeremic M., Stavem P. A new type of inclusion bodies in lymphocytes. Scand J Haematol. 1968;5(2):81–96. doi: 10.1111/j.1600-0609.1968.tb01723.x. [DOI] [PubMed] [Google Scholar]
  6. Imamura M., Block S. R., Mellors R. C. Electron microscopic study of distinctive structures in peripheral blood lymphocytes obtained from twins with systemic lupus erythematosus. Am J Pathol. 1975 Dec;81(3):561–574. [PMC free article] [PubMed] [Google Scholar]
  7. Jondal M., Holm G., Wigzell H. Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells. J Exp Med. 1972 Aug 1;136(2):207–215. doi: 10.1084/jem.136.2.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. McKenna R. W., Parkin J., Kersey J. H., Gajl-Peczalska K. J., Peterson L., Brunning R. D. Chronic lymphoproliferative disorder with unusual clinical, morphologic, ultrastructural and membrane surface marker characteristics. Am J Med. 1977 Apr;62(4):588–596. doi: 10.1016/0002-9343(77)90422-3. [DOI] [PubMed] [Google Scholar]
  9. Payne C. M., Glasser L. The effect of steroids on peripheral blood lymphocytes containing parallel tubular arrays. Am J Pathol. 1978 Sep;92(3):611–618. [PMC free article] [PubMed] [Google Scholar]
  10. Payne C. M., Jones J. F., Sieber O. F., Jr, Fulginiti V. A. Parallel tubular arrays in severe combined immunodeficiency disease: an ultrastructural study of peripheral blood lymphocytes. Blood. 1977 Jul;50(1):55–64. [PubMed] [Google Scholar]
  11. Payne C. M., Nagle R. B. Complement receptors on normal human lymphocytes containing parallel tubular arrays. Am J Pathol. 1980 Jun;99(3):645–666. [PMC free article] [PubMed] [Google Scholar]
  12. Turpin F., Lejeune F., Lortholary P. Inclusions tubulaires dans les lymphocytes d'une leucémie a tricholeucocytes. Pathol Biol (Paris) 1976 Apr;24(4):287–292. [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES