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. 1982 May;35(5):510–516. doi: 10.1136/jcp.35.5.510

Malignant histiocytosis of the intestine: report of three cases with immunological and cytochemical analysis.

P Isaacson, D B Jones, M J Sworn, D H Wright
PMCID: PMC497708  PMID: 6979557

Abstract

Tumour cells from three cases of malignant histiocytosis of the intestine (MHI) have been studied immunologically and cytochemically. The cells did not form E rosettes and showed weak Fc gamma surface receptors. They contained non-specific esterase and acid phosphatase in diffuse granular distribution. In one case tumour cells showed no staining by an immunoperoxidase technique with two monoclonal anti-T cell antibodies but positive staining with a monoclonal anti-Ia-like antibody. The malignant cells from all three cases could be shown to contain alpha-1-antitrypsin. These are the first cases of MHI to have been studied in this way and the results confirm the true histiocytic--that is, monocyte/macrophage, derivation of the tumour cells in this disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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