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. 1982 Aug;35(8):807–811. doi: 10.1136/jcp.35.8.807

Measurement of the fasting urinary hydroxyproline: creatinine ratio in normal adults and its variation with age and sex.

A Hodgkinson, T Thompson
PMCID: PMC497793  PMID: 7107952

Abstract

Conditions for the determination of the fasting urinary hydroxyproline: creatinine ratio (OHPr: Cr ratio) have been examined, using a resin-catalysed hydrolysis and automated colorimetric procedure for the determination of hydroxyproline. Feeding experiments with gelatin showed that hydroxyproline is rapidly absorbed and excreted in the urine and that a 12-hour (overnight) fast is sufficient to ensure correct and reproducible fasting OHPr: Cr ratios. The mean fasting OHPr: Cr ratio decreased slightly with increasing age in both men and premenopausal women but there was no significant difference between the sexes. There was, however, a significant increase in the mean ratio in postmenopausal women. The normal range of fasting OHPr: Cr ratios for men and premenopausal women was found to be 0.003--0.015.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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