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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1982 Oct;35(10):1063–1065. doi: 10.1136/jcp.35.10.1063

Morphometrical analysis of urothelial cells in voided urine of patients with low grade and high grade bladder tumours.

E C Ooms, P J Kurver, M E Boon
PMCID: PMC497883  PMID: 7130416

Abstract

The morphometric differences between the urothelial cells (wet-fixed Papanicolaoustained) in the voided urine of 2 patients with low grade and high grade bladder tumours were measured. The morphometrical data of this learning set resulted in a cytomorphometrical classification rule, which was applied to a test set of 21 cases with low grade and high grade bladder tumours. The results of the cytomorphometrical classification rule correspond very well with the histomorphometrical classification and the histological grade of the parent tumours. The results indicate that it is feasible to classify bladder tumours using the cytomorphometrical data of the exfoliated urothelial cells alone.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beyer-Boon M. E., de Voogt H. J., van der Velde E. A., Brussee J. A., Schaberg A. The efficacy of urinary cytology in the detection of urothelial tumours. Sensitivity and specificity of urinary cytology. Urol Res. 1978;6(1):3–12. doi: 10.1007/BF00257076. [DOI] [PubMed] [Google Scholar]
  2. Boon M. E., Kurver P. H., Baak J. P., Ooms E. C. Morphometric differences between urothelial cells in voided urine of patients with grade I and grade II bladder tumours. J Clin Pathol. 1981 Jun;34(6):612–615. doi: 10.1136/jcp.34.6.612. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Koss L. G. Mapping of the urinary bladder: its impact on the concepts of bladder cancer. Hum Pathol. 1979 Sep;10(5):533–548. doi: 10.1016/s0046-8177(79)80097-0. [DOI] [PubMed] [Google Scholar]
  4. Matsumoto K., Kakizoe T., Mikuriya S., Tanaka T., Kondo I., Umegaki Y. Clinical evaluation of intraoperative radiotherapy for carcinoma of the urinary bladder. Cancer. 1981 Feb 1;47(3):509–513. doi: 10.1002/1097-0142(19810201)47:3<509::aid-cncr2820470314>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
  5. Soloway M. S., Ikard M., Ford K. Cis-diamminedichloroplatinum (II) in locally advanced and metastatic urothelial cancer. Cancer. 1981 Feb 1;47(3):476–480. doi: 10.1002/1097-0142(19810201)47:3<476::aid-cncr2820470309>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
  6. Tribukait B., Esposti P. L. Quantitative flow-microfluorometric analysis of the DNA in cells from neoplasms of the urinary bladder: correlation of aneuploidy with histological grading and the cytological findings. Urol Res. 1978;6(4):201–205. doi: 10.1007/BF00262618. [DOI] [PubMed] [Google Scholar]
  7. Tribukait B., Gustafson H., Esposti P. Ploidy and proliferation in human bladder tumors as measured by flow-cytofluorometric DNA-analysis and its relations to histopathology and cytology. Cancer. 1979 May;43(5):1742–1751. doi: 10.1002/1097-0142(197905)43:5<1742::aid-cncr2820430525>3.0.co;2-c. [DOI] [PubMed] [Google Scholar]

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