Figure 3.

D-JNKI delays LPS-induced preterm delivery and increases pup survival. Timed pregnant CD-1 mice were injected on gestation day 16 with 1.0 μg Salmonella abortus LPS (n=7) or LPS together with 5 μg of D-JNKI (n=8) or with 5 μg of D-JNKI alone (n=8). Delivery of the newborn pups and their survival rate was monitored every 6 h. D-JNKI led to a significant increase in time to delivery as well as increased pup survival. Data represent the mean (±s.e.m.) of n animals at each group. **P<0.01, Kruskal-Wallis equality-of-population rank test.