Figure 6.

D-JNKI inhibits LPS-induced JNK/JNK3 and caspase-3 activation in the fetal brain. Pup brain extracts collected at 6 h following injection with 1.0 μg of Salmonella abortus LPS alone, LPS together with 5 μg of D-JNKI, or with 5 μg of D-JNKI alone were analysed for (A) JNK/JNK3 and (B) cleaved caspase-3 activation. Data represent the mean (±s.e.m.) of three animals at each data point. The difference between LPS alone or together with D-JNKI was statistically significant by ANOVA (**P<0.05).