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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Hypertension. 2016 Jul 5;68(3):621–629. doi: 10.1161/HYPERTENSIONAHA.116.07328

Figure 2. Effects of rs2727563 and rs12604940 polymorphisms on the BP responses of whites treated with HCTZ in the PEAR HCTZ monotherapy and HCTZ add-on.

Figure 2

A) rs2727563 on SBP responses in PEAR monotherapy and PEAR HCTZ add-on. B) rs2727563 on DBP response in the PEAR monotherapy and PEAR HCTZ add-on. C) rs12604940 on SBP response in PEAR monotherapy and PEAR HCTZ add-on. D) rs12604940 on DBP response in the PEAR monotherapy and PEAR HCTZ add-on. BP responses were adjusted for baseline BP, age, sex, and principal components 1 and 2. P-values represented are for contrast of adjusted means between different genotype groups. Error bars represent standard error of the mean. *One sided p-value based on a one-sided hypothesis tested in the replication study.