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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Hypertension. 2016 Jul 5;68(3):621–629. doi: 10.1161/HYPERTENSIONAHA.116.07328

Figure 4. Effects of rs13262930 polymorphism on the BP response of whites treated with HCTZ in the PEAR HCTZ monotherapy and PEAR HCTZ add-on.

Figure 4

A) SBP response in the PEAR HCTZ monotherapy. B) DBP response in the PEAR HCTZ monotherapy. C) Replicating the effect on SBP response in the PEAR HCTZ add-on. D) Replicating the effect on DBP response in the PEAR HCTZ add-on. BP responses were adjusted for baseline BP, age, sex and principal components 1 and 2. P-values represented are for contrast of adjusted means between different genotype groups. Error bars represent standard error of the mean. *One sided p-value based on a one-sided hypothesis tested in the replication study.