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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1983 Jul;36(7):798–803. doi: 10.1136/jcp.36.7.798

Comparison of serum amyloid A protein and C-reactive protein concentrations in cancer and non-malignant disease.

J G Raynes, E H Cooper
PMCID: PMC498391  PMID: 6863571

Abstract

Serum amyloid A (SAA) concentrations correlate well with C-reactive protein (CRP) concentrations. However, SAA is sometimes raised in disease when CRP is normal. This appears to occur more often in certain diseases such as rheumatoid arthritis, primary biliary cirrhosis and chronic active hepatitis. SAA concentrations did not distinguish between cancer with and without metastases as previously indicated, although mean concentrations were higher in more advanced tumours. Despite the higher sensitivity of SAA over CRP in the inflammatory response, SAA has little advantage over CRP in the assessment of malignant disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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