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. 1984 Jan;37(1):59–64. doi: 10.1136/jcp.37.1.59

Splenic siderosis and parenteral iron dextran in maintenance haemodialysis patients.

J A Murray, D N Slater, M A Parsons, M Fox, S Smith, M M Platts
PMCID: PMC498619  PMID: 6707221

Abstract

The histological features of 40 spleens surgically removed from maintenance haemodialysis patients are reported. Twenty-four of the 40 (60%) showed massive iron loading and a significant direct correlation was found between iron loading and the amount of intravenous iron dextran administered. Since parenteral iron dextran appears to be a major factor in causing iron overload in haemodialysis patients its use as a method of iron replacement in these patients would appear inappropriate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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