Abstract
Tumour eosinophilia is an uncommon but striking phenomenon which has been found in many tumours, mostly of large cell type or squamous differentiation. The incidence, appearance and importance of tumour eosinophilia in the bladder are described. Eosinophilia is commoner in deeply invasive tumours and in tumours showing squamous metaplasia. Transitional cell carcinomas with eosinophilia have a better prognosis than those without, but this improvement is not seen in squamous cell carcinomas of the bladder. When eosinophilia is found on superficial biopsies of a bladder tumour, the possibility of muscle invasion should be considered.
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Selected References
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- Bostrom S. G., Hart W. R. Carcinomas of the cervix with intense stromal eosinophilia. Cancer. 1981 Jun 15;47(12):2887–2893. doi: 10.1002/1097-0142(19810615)47:12<2887::aid-cncr2820471223>3.0.co;2-3. [DOI] [PubMed] [Google Scholar]
- Goetzl E. J., Tashjian A. H., Jr, Rubin R. H., Austen K. F. Production of a low molecular weight eosinophil polymorphonuclear leukocyte chemotactic factor by anaplastic squamous cell carcinomas of human lung. J Clin Invest. 1978 Mar;61(3):770–780. doi: 10.1172/JCI108991. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hellstrom H. R., Davis B. K., Shonnard J. W. Eosinophilic cystitis. A study of 16 cases. Am J Clin Pathol. 1979 Nov;72(5):777–784. doi: 10.1093/ajcp/72.5.777. [DOI] [PubMed] [Google Scholar]
- Inoue T., Iwasaki K., Chihara T., Torisu M. Cervical carcinoma and eosinophil I. Eosinophil chemotactic factor derived from invasive cervical carcinoma with eosinophil infiltration. Clin Immunol Immunopathol. 1981 Dec;21(3):320–331. doi: 10.1016/0090-1229(81)90221-x. [DOI] [PubMed] [Google Scholar]
- Lowe D., Jorizzo J., Hutt M. S. Tumour-associated eosinophilia: a review. J Clin Pathol. 1981 Dec;34(12):1343–1348. doi: 10.1136/jcp.34.12.1343. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Slungaard A., Ascensao J., Zanjani E., Jacob H. S. Pulmonary carcinoma with eosinophilia. Demonstration of a tumor-derived eosinophilopoietic factor. N Engl J Med. 1983 Sep 29;309(13):778–781. doi: 10.1056/NEJM198309293091307. [DOI] [PubMed] [Google Scholar]
- Tiltman A. J. Eosinophilic infiltrates in carcinoma of the urinary bladder unassociated with schistosomiasis. J Pathol. 1978 Oct;126(2):79–83. doi: 10.1002/path.1711260204. [DOI] [PubMed] [Google Scholar]
- Wasserman S. I., Goetzl E. J., Ellman L., Austen K. F. Tumor-associated eosinophilotactic factor. N Engl J Med. 1974 Feb 21;290(8):420–424. doi: 10.1056/NEJM197402212900802. [DOI] [PubMed] [Google Scholar]