Abstract
Infected ulcerated malignant tumours are often foul smelling and covered with necrotic tissue. We have studied 70 patients with infected ulcers; 30 of the underlying lesions in these patients were carcinoma of the breast, and 19 were a variety of skin cancers. Anaerobes were the predominant organisms isolated from individual ulcers. Of the 179 anaerobes isolated, 37 were Bacteroides asaccharolyticus, 31 each were B melaninogenicus and anaerobic streptococci, 29 B fragilis, and 17 B ureolyticus. Among the facultative organisms Escherichia coli was the commonest and was isolated mainly from patients with carcinoma of the breast. Most infections were mixed, yielding both anaerobes and aerobes and this made interpretation of the role of individual pathogens difficult to assess.
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Selected References
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- Ashby E. C., Rees M., Dowding C. H. Prophylaxis against systemic infection after transrectal biopsy for suspected prostatic carcinoma. Br Med J. 1978 Nov 4;2(6147):1263–1264. doi: 10.1136/bmj.2.6147.1263. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Duerden B. I., Collee J. G., Brown R., Deacon A. G., Holbrook W. P. A scheme for the identification of clinical isolates of Gram-negative anaerobic bacilli by conventional bacteriological tests. J Med Microbiol. 1980 May;13(2):231–245. doi: 10.1099/00222615-13-2-231. [DOI] [PubMed] [Google Scholar]
- Duerden B. I. The identification of gram-negative anaerobic bacilli isolated from clinical infections. J Hyg (Lond) 1980 Apr;84(2):301–313. doi: 10.1017/s0022172400026802. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Duerden B., Bennet K. W., Faulkner J. Isolation of Bacteroides ureolyticus (B corrodens) from clinical infections. J Clin Pathol. 1982 Mar;35(3):309–312. doi: 10.1136/jcp.35.3.309. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Felner J. M., Dowell V. R., Jr "Bacteroides" bacteremia. Am J Med. 1971 Jun;50(6):787–796. doi: 10.1016/0002-9343(71)90187-2. [DOI] [PubMed] [Google Scholar]
- Holbrook W. P., Ogston S. A., Ross P. W. A method for the isolation of Bacteroides melaninogenicus from the human mouth. J Med Microbiol. 1978 May;11(2):203–207. doi: 10.1099/00222615-11-2-203. [DOI] [PubMed] [Google Scholar]
- Klastersky J., Coppens L., Mombelli G. Anaerobic infection in cancer patients: comparative evaluation of clindamycin and cefoxitin. Antimicrob Agents Chemother. 1979 Sep;16(3):366–371. doi: 10.1128/aac.16.3.366. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Klastersky J., Husson M., Weerts-Ruhl D., Daneau D. Anaerobic wound infections in cancer patients: comparative trial of clindamycin, tinidazole, and doxycycline. Antimicrob Agents Chemother. 1977 Nov;12(5):563–570. doi: 10.1128/aac.12.5.563. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lagast H., Klastersky J. Anaerobic infections in cancer patients--a retrospective analysis of clindamycin, tinidazole, doxycycline, cefoxitin and lamoxactam. Infection. 1982;10(3):144–148. doi: 10.1007/BF01640764. [DOI] [PubMed] [Google Scholar]
- Lagast H., Meunier-Carpentier F., Klastersky J. Moxalactam treatment of anaerobic infections in cancer patients. Antimicrob Agents Chemother. 1982 Oct;22(4):604–610. doi: 10.1128/aac.22.4.604. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MCHENRY M. C., WELLMAN W. E., MARTIN W. J. Bacteremia due to Bacteroides. Review of 11 cases. Arch Intern Med. 1961 Apr;107:572–577. doi: 10.1001/archinte.1961.03620040098011. [DOI] [PubMed] [Google Scholar]
- Rotimi V. O., Duerden B. I. The development of the bacterial flora in normal neonates. J Med Microbiol. 1981 Feb;14(1):51–62. doi: 10.1099/00222615-14-1-51. [DOI] [PubMed] [Google Scholar]
- Rotimi V. O., Faulkner J., Duerden B. I. Rapid methods for identification of clinical isolates of Gram-negative anaerobic bacilli. Med Lab Sci. 1980 Oct;37(4):331–339. [PubMed] [Google Scholar]
- Sinkovics J. G., Smith J. P. Septicemia with bacteroides in patients with malignant disease. Cancer. 1970 Mar;25(3):663–671. doi: 10.1002/1097-0142(197003)25:3<663::aid-cncr2820250323>3.0.co;2-b. [DOI] [PubMed] [Google Scholar]