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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1984 Jun;37(6):601–606. doi: 10.1136/jcp.37.6.601

Increased numbers of IgE containing cells in gastric and duodenal biopsies. An expression of food allergy secondary to chronic inflammation?

J P van Spreeuwel, J Lindeman, J van Maanen, C J Meyer
PMCID: PMC498830  PMID: 6373835

Abstract

Gastric and duodenal biopsies from 2543 patients with abdominal complaints were sent to the Department of Pathology of the Stichting Samenwerking Delftse Ziekenhuizen in 1980 and 1981 and screened for plasma cells containing IgE using an indirect immunoperoxidase technique. Increased numbers of IgE containing cells were found in 2.6% of the patients. These patients all suffered from a variety of chronic non-specific inflammatory disorders of the upper gastrointestinal tract. No specific clinical, endoscopical, or histological picture could be found. The results suggest that increased numbers of plasma cells containing IgE in biopsies from the upper gastrointestinal tract are an expression of IgE mediated type I allergy presumably to food constituents as a secondary complication of chronic non-specific gastric and duodenal inflammation in these patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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