Table 2.
Chemokine and cytokine mRNA changes in the SVZ after TMEV.
| Gene Name | Gene symbol | C57BL/6 | SJL/J |
|---|---|---|---|
| Complement component 3 | C3 | 66.8±13.9 | 4.2±1.0 |
| Complement component 3a receptor 1 | C3ar1 | 13.1±1.1 | 5.7±0.6 |
| Chemokine (C-C) motif ligand 1 | Ccl1 | 11.8±0.9 | 2.9±0.7 |
| Chemokine (C-C) motif ligand 11 | Ccl11 | 20.4±3.4 | 1.1±0.8 |
| Chemokine (C-C) motif ligand 12 | Ccl12 | 63.9±18.2 | 45.5±5.1 |
| Chemokine (C-C) motif ligand 2 | Ccl2 | 277.6±47.4 | 43.5±1.5 |
| Chemokine (C-C) motif ligand 22 | Ccl22 | 14.1±4.4 | 2.2±0.3 |
| Chemokine (C-C) motif ligand 5 | Ccl5 | 257.8±67.8 | 639.4±206.3 |
| Chemokine (C-C) motif ligand 7 | Ccl7 | 354.3±29.9 | 99.5±49.0 |
| Chemokine (C-C) motif ligand 8 | Ccl8 | 29.2±11.0 | 148.8±14.8 |
| Chemokine (C-C)motif receptor 1 | Ccr1 | 6.9±2.3 | 2.3±0.1 |
| Chemokine (C-C)motif receptor 2 | Ccr2 | 17.3±6.3 | 6.3±1.6 |
| Chemokine (C-C)motif receptor 3 | Ccr3 | 6.4±0.7 | 3.0±0.4 |
| Chemokine (C-C)motif receptor 4 | Ccr4 | 4.0±1.4 | 2.0±0.1 |
| Chemokine (C-C)motif receptor 7 | Ccr7 | 4.2±0.7 | 1.6±0.0 |
| Chemokine (C-X-C motif) ligand 10 | Cxcl10 | 798.0±139.5 | 70.9±14.7 |
| Chemokine (C-X-C motif) ligand 11 | Cxcl11 | 46.8±3.7 | 61.3±9.2 |
| Chemokine (C-X-C motif) ligand 9 | Cxcl9 | 626.0±317.3 | 254.8±16.2 |
| Interferon gamma | Ifnγ | 25.8±6.3 | 6.4±0.2 |
| Interleukin 10 | Il10 | 5.8±1.1 | 13.9±0.9 |
| Interleukin 8 receptor acc. protein | Il18rap | 12.3±4.8 | 2.5±0.8 |
| Interleukin 1 beta | Il1β | 30.7±12.1 | 8.3±2.6 |
| Toll-like receptor 2 | Tlr2 | 13.6±1.8 | 8.6±8.6 |
Values are TMEV-induced fold increases±sd. Averages for triplicate samples of 7 dpi TMEV versus sham. Table shows genes that are present on SABiosciences RT-PCR array PAMM-077. Only genes which showed 4 or more fold increases in C57BL/6 mice are shown. Boxes shaded in grey are SJL genes that showed greater than 4 fold increase.