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. 1984 Jun;37(6):633–638. doi: 10.1136/jcp.37.6.633

Rapid processing of fetal skin for prenatal diagnosis by light and electron microscopy.

R A Eady, D B Gunner, M J Tidman, K H Nicolaides, C H Rodeck
PMCID: PMC498836  PMID: 6725611

Abstract

A method has been developed for rapid processing of fetal skin for prenatal diagnosis of hereditary skin diseases by light and electron microscopy. Fixation, dehydration, embedding, and polymerisation can be achieved in about 5 h. The quality of tissue preservation compares favourably with that produced by slower conventional techniques. This procedure may provoke a wider interest in the potential use of fetal skin biopsy in prenatal diagnosis, especially if identification of structural abnormalities is a feasible alternative to more time consuming biochemical analysis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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