Abstract
Viral lymphadenitis may lead to a histological appearance that can simulate malignancy. The histological features of herpes simplex lymphadenitis have not previously been described in detail. We report a case of proved herpes simplex lymphadenitis in a 30 year old man which was characterised by a pronounced proliferation of immunoblasts. The microscopical findings are described and the published work is reviewed.
Full text
PDF



Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Braun R. W., Teute H. K., Kirchner H., Munk K. Replication of herpes simplex virus in human T lymphocytes: characterization of the viral target cell. J Immunol. 1984 Feb;132(2):914–919. [PubMed] [Google Scholar]
- Dorfman R. F., Warnke R. Lymphadenopathy simulating the malignant lymphomas. Hum Pathol. 1974 Sep;5(5):519–550. doi: 10.1016/s0046-8177(74)80005-5. [DOI] [PubMed] [Google Scholar]
- Dorman J. M. Herpetic lymphangitis in a student population. J Adolesc Health Care. 1982 Aug;3(1):49–50. doi: 10.1016/s0197-0070(82)80029-6. [DOI] [PubMed] [Google Scholar]
- Edington N., Patel J., Russell P. H., Plowright W. The nature of the acute lymphoid proliferation in rabbits infected with the herpes virus of bovine malignant catarrhal fever. Eur J Cancer. 1979 Dec;15(12):1515–1522. doi: 10.1016/0014-2964(79)90033-1. [DOI] [PubMed] [Google Scholar]
- Hartsock R. J. Postvaccinial lymphadenitis. Hyperplasia of lymphoid tissue that simulates malignant lymphomas. Cancer. 1968 Apr;21(4):632–649. doi: 10.1002/1097-0142(196804)21:4<632::aid-cncr2820210415>3.0.co;2-o. [DOI] [PubMed] [Google Scholar]
- Hillard P., Seeds J., Cefalo R. Disseminated herpes simplex in pregnancy: two cases and a review. Obstet Gynecol Surv. 1982 Jul;37(7):449–453. doi: 10.1097/00006254-198207000-00002. [DOI] [PubMed] [Google Scholar]
- Howard W. R., Taylor J. S., Steck W. D. Lymphatic complications of manual herpes simplex infection. Cutis. 1979 May;23(5):580–583. [PubMed] [Google Scholar]
- Jennings S. R., Rice P. L., Pan S., Knowles B. B., Tevethia S. S. Recognition of herpes simplex virus antigens on the surface of mouse cells of the H-2b haplotype by virus-specific cytotoxic T lymphocytes. J Immunol. 1984 Jan;132(1):475–481. [PubMed] [Google Scholar]
- Rossiter P. B. Proliferation of T lymphoblasts in rabbits fatally infected with the herpes virus of malignant catarrhal fever. Clin Exp Immunol. 1983 Nov;54(2):547–553. [PMC free article] [PubMed] [Google Scholar]
- Rouse B. T., Wagner H. Frequency of herpes simplex virus-specific cytotoxic T lymphocyte precursors in lymph node cells of infected mice. Immunology. 1984 Jan;51(1):57–64. [PMC free article] [PubMed] [Google Scholar]
- Salvador A. H., Harrison E. G., Jr, Kyle R. A. Lymphadenopathy due to infectious mononucleosis: its confusion with malignant lymphoma. Cancer. 1971 May;27(5):1029–1040. doi: 10.1002/1097-0142(197105)27:5<1029::aid-cncr2820270505>3.0.co;2-w. [DOI] [PubMed] [Google Scholar]
- Schäffer R., Ormanns W., Pfeifer U. Zur autoptischen Diagnostik von Herpes simplex infektionen. Verh Dtsch Ges Pathol. 1981;65:230–234. [PubMed] [Google Scholar]


