In the March issue of Thyroid, (vol. 25, no. 3; 292–299), the article “Long-Term Outcome of Loss-of-Function Mutations in Thyrotropin Receptor Gene” by Tenenbaum-Rakover et al. (1) requires a correction.
There is a one digit error in the reported novel mutant nucleotide producing the mutant RTSH R450C. This error appears in the last line of Table 2, page 295. It should read “1348” rather than “1347.”
Table 2.
Summary of Identified TSHR Gene Mutations
| DNA | Protein | Exon | No. of alleles | Reference |
|---|---|---|---|---|
| c.202C > T | p.P68S | 2 | 5 | 10 |
| c.269A > C | p.Q90P | 3 | 6 | 11 |
| c.484C > G | p.P162A | 6 | 6 | 3 |
| c.790C > T | p.P264S | 9 | 6 | 11 |
| c.1957C > G | p.L653V | 10 | 23 | 10 |
| c.1348C > T | p.R450C | 10 | 2 | Novel |
The online version of the article has been corrected to reflect this change.
Reference
- 1.Tenenbaum-Rakover Y, Almashanu S, Hess O, Admoni O, Hag-Dahood Mahameed A, Schwartz A, Allon-Shalev S, Bercovich D, Refetoff S. 2015. Long-term outcome of loss-of-function mutations in thyrotropin receptor. Thyroid 25:292–299 [DOI] [PMC free article] [PubMed] [Google Scholar]
