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. 1984 Dec;37(12):1339–1342. doi: 10.1136/jcp.37.12.1339

The platelet defect in acute myeloid leukaemia.

B E Woodcock, P C Cooper, P R Brown, C Pickering, D A Winfield, F E Preston
PMCID: PMC499013  PMID: 6595273

Abstract

In a study of platelets from 13 patients with acute myeloid leukaemia abnormal aggregation and release reactions were found. A previously unrecognised quantitative defect of thromboxane B2 production may, at least in part, explain these findings. In contrast to a previous report, we were unable to show a convincing storage pool defect in these platelets. The platelet membrane glycoproteins were largely normal.

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Selected References

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