Abstract
The peripheral lymphocytes of a patient with prodromal acquired immune deficiency syndrome contained giant multivesicular bodies. These were specifically stained by immuno-gold labelled polyclonal antibodies against the major core protein p24 of bovine leukaemia virus and human T cell leukaemia virus I. Moreover, the patient's serum was positive for bovine leukaemia virus by the ELISA method.
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- Anderson M. G., Dixey J., Key P., Ellis D. S., Tovey G., McCaul T. F., Murray-Lyon I. M., Gazzard B., Lawrence A., Evans B. Persistent lymphadenopathy in homosexual men: a clinical and ultrastructural study. Lancet. 1984 Apr 21;1(8382):880–882. doi: 10.1016/s0140-6736(84)91342-4. [DOI] [PubMed] [Google Scholar]
- Bex F., Bruck C., Mammerickx M., Portetelle D., Ghysdael J., Cleuter Y., Leclercq M., Dekegel D., Burny A. Humoral antibody response to bovine leukemia virus infection in cattle and sheep. Cancer Res. 1979 Mar;39(3):1118–1123. [PubMed] [Google Scholar]
- Feremans W. W., Neve P., Caudron M. IgM lambda cytoplasmic crystals in three cases of immunocytoma: a clinical, cytochemical, and ultrastructural study. J Clin Pathol. 1978 Mar;31(3):250–258. doi: 10.1136/jcp.31.3.250. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Feremans W., Menu R., Dustin P., Clumeck N., Marcelis L., Hupin J. Virus-like particles in lymphocytes of seven cases of AIDS in Black Africans. Lancet. 1983 Jul 2;2(8340):52–53. doi: 10.1016/s0140-6736(83)90040-5. [DOI] [PubMed] [Google Scholar]
- Garzon S., Bendayan M., Kurstak E. Ultrastructural localization of viral antigens using the protein A-gold technique. J Virol Methods. 1982 Oct;5(2):67–73. doi: 10.1016/0166-0934(82)90083-0. [DOI] [PubMed] [Google Scholar]
- Ghysdael J., Kettmann R., Burny A. Translation of bovine leukemia virus virion RNAs in heterologous protein-synthesizing systems. J Virol. 1979 Mar;29(3):1087–1098. doi: 10.1128/jvi.29.3.1087-1098.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Marx P. A., Maul D. H., Osborn K. G., Lerche N. W., Moody P., Lowenstine L. J., Henrickson R. V., Arthur L. O., Gilden R. V., Gravell M. Simian AIDS: isolation of a type D retrovirus and transmission of the disease. Science. 1984 Mar 9;223(4640):1083–1086. doi: 10.1126/science.6695196. [DOI] [PubMed] [Google Scholar]
- Popovic M., Sarngadharan M. G., Read E., Gallo R. C. Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science. 1984 May 4;224(4648):497–500. doi: 10.1126/science.6200935. [DOI] [PubMed] [Google Scholar]
- Portetelle D., Bruck C., Mammerickx M., Burny A. In animals infected by bovine leukemia virus (BLV) antibodies to envelope glycoprotein gp51 are directed against the carbohydrate moiety. Virology. 1980 Aug;105(1):223–233. doi: 10.1016/0042-6822(80)90169-5. [DOI] [PubMed] [Google Scholar]
- Portetelle D., Bruck C., Mammerickx M., Burny A. Use of monoclonal antibody in an ELISA test for the detection of antibodies to bovine leukaemia virus. J Virol Methods. 1983 Jan;6(1):19–29. doi: 10.1016/0166-0934(83)90064-2. [DOI] [PubMed] [Google Scholar]
- Schaff Z., Tabor E., Jackson D. R., Gerety R. J. AIDS-associated ultrastructural changes. Lancet. 1983 Jun 11;1(8337):1336–1336. doi: 10.1016/s0140-6736(83)92447-9. [DOI] [PubMed] [Google Scholar]
- Sidhu G. S., Stahl R. E., El-Sadr W., Zolla-Pazner S. Ultrastructural markers of AIDS. Lancet. 1983 Apr 30;1(8331):990–991. doi: 10.1016/s0140-6736(83)92114-1. [DOI] [PubMed] [Google Scholar]
- Thomas Y., Sosman J., Irigoyen O., Friedman S. M., Kung P. C., Goldstein G., Chess L. Functional analysis of human T cell subsets defined by monoclonal antibodies. I. Collaborative T-T interactions in the immunoregulation of B cell differentiation. J Immunol. 1980 Dec;125(6):2402–2408. [PubMed] [Google Scholar]
- Ultrastructural markers in AIDS. Lancet. 1983 Jul 30;2(8344):284–284. [PubMed] [Google Scholar]
- Ultrastructure of AIDS lymph nodes. N Engl J Med. 1983 Nov 10;309(19):1188–1190. doi: 10.1056/NEJM198311103091914. [DOI] [PubMed] [Google Scholar]
- Vilmer E., Barre-Sinoussi F., Rouzioux C., Gazengel C., Brun F. V., Dauguet C., Fischer A., Manigne P., Chermann J. C., Griscelli C. Isolation of new lymphotropic retrovirus from two siblings with haemophilia B, one with AIDS. Lancet. 1984 Apr 7;1(8380):753–757. doi: 10.1016/s0140-6736(84)91275-3. [DOI] [PubMed] [Google Scholar]