Abstract
The diagnosis of gastro-oesophageal candidiasis by brush cytology was studied in two groups. In eight immunosuppressed patients clinically suspected to have candidiasis, fungal infection was confirmed on six occasions, and a diagnosis of herpetic oesophagitis was established in the other two cases. Among 482 gastric and oesophageal brushings clinically unsuspected candidiasis was found on a further 12 occasions. Coexisting abnormalities including carcinoma, lymphoma, and postradiation oesophagitis were also identified by brushing. Of the 18 patients with cytologically confirmed candidiasis, endoscopic biopsies were available in 13, but histological diagnosis of fungal infection was possible in only two (15.5%).
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Eras P., Goldstein M. J., Sherlock P. Candida infection of the gastrointestinal tract. Medicine (Baltimore) 1972 Sep;51(5):367–379. doi: 10.1097/00005792-197209000-00002. [DOI] [PubMed] [Google Scholar]
- Hopkin J. M., Turney J. H., Young J. A., Adu D., Michael J. Rapid diagnosis of obscure pneumonia in immunosuppressed renal patients by cytology of alveolar lavage fluid. Lancet. 1983 Aug 6;2(8345):299–301. doi: 10.1016/s0140-6736(83)90287-8. [DOI] [PubMed] [Google Scholar]
- Katzenstein A. L., Maksem J. Candidal infection of gastric ulcers. Histology, incidence, and clinical significance. Am J Clin Pathol. 1979 Feb;71(2):137–141. doi: 10.1093/ajcp/71.2.137. [DOI] [PubMed] [Google Scholar]
- Kodsi B. E., Wickremesinghe C., Kozinn P. J., Iswara K., Goldberg P. K. Candida esophagitis: a prospective study of 27 cases. Gastroenterology. 1976 Nov;71(5):715–719. [PubMed] [Google Scholar]
- Minoli G., Terruzzi V., Butti G., Frigerio G., Rossini A. Gastric candidiasis: an endoscopic and histological study in 26 patients. Gastrointest Endosc. 1982 May;28(2):59–61. doi: 10.1016/s0016-5107(82)72998-0. [DOI] [PubMed] [Google Scholar]
- Myerowitz R. L., Pazin G. J., Allen C. M. Disseminated candidiasis. Changes in incidence, underlying diseases, and pathology. Am J Clin Pathol. 1977 Jul;68(1):29–38. doi: 10.1093/ajcp/68.1.29. [DOI] [PubMed] [Google Scholar]
- Scott B. B., Jenkins D. Gastro-oesophageal candidiasis. Gut. 1982 Feb;23(2):137–139. doi: 10.1136/gut.23.2.137. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Young J. A., Hopkin J. M., Cuthbertson W. P. Pulmonary infiltrates in immunocompromised patients: diagnosis by cytological examination of bronchoalveolar lavage fluid. J Clin Pathol. 1984 Apr;37(4):390–397. doi: 10.1136/jcp.37.4.390. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Young J. A., Hughes H. E., Lee F. D. Evaluation of endoscopic brush and biopsy touch smear cytology and biopsy histology in the diagnosis of carcinoma of the lower oesophagus and cardia. J Clin Pathol. 1980 Sep;33(9):811–814. doi: 10.1136/jcp.33.9.811. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Young J. A., Hughes H. E. Three year trial of endoscopic cytology of the stomach and duodenum. Gut. 1980 Mar;21(3):241–246. doi: 10.1136/gut.21.3.241. [DOI] [PMC free article] [PubMed] [Google Scholar]