Table 1.
Summary of the levels of N 2-ethyl-dG measured in the three tissues in monkeys exposed to various amounts of ethanol and in controls
| Sample no. | Gender | Cheek DNA N 2-ethyl-dG (fmol/µmol dG) | Oesophagus DNA N 2-ethyl-dG (fmol/µmol dG) | Mammary gland DNA N 2-ethyl-dG (fmol/µmol dG) | Average EtOH consumption in 22h (g/kg) |
|---|---|---|---|---|---|
| 1 | M | 757 | 396 | – | 1.80 |
| 2 | M | 460 | 292 | – | 3.10 |
| 3 | M | 722 | 152 | – | 2.30 |
| 4 | M | 900 | 633 | – | 2.80 |
| 5a | M | 1503 | 238 | – | 3.00 |
| 6 | M | 310 | 184 | – | 1.90 |
| 7 | M | 427 | 135 | – | 1.90 |
| 8 | M | 556 | 167 | – | 3.30 |
| 9 | M | 164 | 216 | – | 2.40 |
| 10 | M | 401 | 150 | – | 1.40 |
| 11 | M | 690 | 301 | – | 1.80 |
| 12 | M | 109 | 142 | – | 2.06 |
| 13 | M | 116 | 227 | – | 2.26 |
| 14 | F | 115 | 99 | 167 | 1.00 |
| 15 | F | 67 | 74 | 106 | 4.02 |
| 16 | F | 81 | 99 | 91 | 1.77 |
| 17 | F | 226 | 116 | 84 | 2.81 |
| 18 | F | 77 | 91 | 93 | 1.45 |
| 19 | M | 234 | 191 | – | 0.00 |
| 20 | M | 354 | 141 | – | 0.00 |
| 21 | M | 85 | 145 | – | 0.00 |
| 22 | M | 372 | 189 | – | 0.00 |
| 23 | M | 267 | 190 | – | 0.00 |
| 24 | M | 72 | 142 | – | 0.00 |
| 25 | M | 78 | 100 | – | 0.00 |
| 26 | M | 65 | 101 | – | 0.00 |
| 27 | F | 35 | 46 | 129 | 0.00 |
| 28 | F | 55 | 55 | 84 | 0.00 |
| 29 | F | 48 | 128 | 150 | 0.00 |
aSample with the highest amount of N 2-ethyl-dG and quantifiable levels of Cro-dG: 2.1fmol/µmol dG of (6S, 8S) Cro-dG and 2fmol/µmol dG of (6R, 8R) Cro-dG.