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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1985 Sep;38(9):995–1001. doi: 10.1136/jcp.38.9.995

Membrane phenotypic studies in B cell lymphoproliferative disorders.

C S Scott, H J Limbert, I D MacKarill, B E Roberts
PMCID: PMC499348  PMID: 2413082

Abstract

A total of 398 cases of B cell lymphoproliferative disease were phenotypically characterised by membrane mouse red blood cell (MRBC) receptor, surface immunoglobulin, common acute lymphoblastic leukaemia (CALLA), and FMC7 and T1 monoclonal antibody studies. Relations between chronic lymphocytic leukaemia (CLL), prolymphocytic leukaemia (PLL), and "prolymphocytoid" CLL variants were examined with particular reference to the expression of FMC7. In addition, the reactivity of TU1 monoclonal antibody with B cell disorders was established. The results suggest that despite some heterogeneity most cases may be characterised by their phenotypic patterns and that these investigations provide a reproducible basis for classification.

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Selected References

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