Skip to main content
NCBI home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1985 Sep;38(9):1055–1058. doi: 10.1136/jcp.38.9.1055

Effect of temperature on antimicrobial susceptibilities of Pseudomonas maltophilia.

P F Wheat, T G Winstanley, R C Spencer
PMCID: PMC499358  PMID: 4044874

Abstract

After a case of peritonitis caused by Pseudomonas maltophilia had occurred 20 strains of the organism were investigated and the minimum inhibitory concentrations of a variety of antibiotics determined at 30 degrees C and 37 degrees C. There was a significant difference in susceptibility between 30 degrees C (most resistant) and 37 degrees C (most susceptible) for aminoglycosides and polymyxin B. No difference was seen with the other agents or in strains of Ps aeruginosa and Enterobacteriaceae tested under similar conditions. The possible mechanisms of this phenomenon are discussed below.

Full text

PDF
1055

Images in this article

1056Image
on p.1056

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Annear D. I., Macculloch D. Letter: Cold-sensitive strain of Pseudomonas aeruginosa from urinary-tract infection. Lancet. 1974 Dec 7;2(7893):1382–1382. doi: 10.1016/s0140-6736(74)92247-8. [DOI] [PubMed] [Google Scholar]
  2. Bell R. M., Mavis R. D., Vagelos P. R. Altered phospholipid metabolism in a temperature-sensitive mutant of Escherichia coli, CR 34 T 46 . Biochim Biophys Acta. 1972 Aug 11;270(4):504–512. [PubMed] [Google Scholar]
  3. Dunnick J. K., O'Leary W. M. Correlation of bacteria lipid composition with antibiotic resistance. J Bacteriol. 1970 Mar;101(3):892–900. doi: 10.1128/jb.101.3.892-900.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Farrell J., Rose A. Temperature effects on microorganisms. Annu Rev Microbiol. 1967;21:101–120. doi: 10.1146/annurev.mi.21.100167.000533. [DOI] [PubMed] [Google Scholar]
  5. Fass R. J. In vitro activity of cefoperazone against nonfermenters and Aeromonas hydrophila. Antimicrob Agents Chemother. 1980 Sep;18(3):483–486. doi: 10.1128/aac.18.3.483. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Felegie T. P., Yu V. L., Rumans L. W., Yee R. B. Susceptibility of Pseudomonas maltophilia to antimicrobial agents, singly and in combination. Antimicrob Agents Chemother. 1979 Dec;16(6):833–837. doi: 10.1128/aac.16.6.833. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Fenton P. Laboratory diagnosis of peritonitis in patients undergoing continuous ambulatory peritoneal dialysis. J Clin Pathol. 1982 Nov;35(11):1181–1184. doi: 10.1136/jcp.35.11.1181. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Fischer J. J. Pseudomonas maltophilia endocarditis after replacement of the mitral valve: a case study. J Infect Dis. 1973 Nov;128(Suppl):771–773. doi: 10.1093/infdis/128.supplement_3.s771. [DOI] [PubMed] [Google Scholar]
  9. Gilardi G. L. Infrequently encountered Pseudomonas species causing infection in humans. Ann Intern Med. 1972 Aug;77(2):211–215. doi: 10.7326/0003-4819-77-2-211. [DOI] [PubMed] [Google Scholar]
  10. HUGH R., RYSCHENKOW E. Pseudomonas maltophilia, an alcaligenes-like species. J Gen Microbiol. 1961 Sep;26:123–132. doi: 10.1099/00221287-26-1-123. [DOI] [PubMed] [Google Scholar]
  11. Holmes B., Lapage S. P., Easterling B. G. Distribution in clinical material and identification of Pseudomonas maltophilia. J Clin Pathol. 1979 Jan;32(1):66–72. doi: 10.1136/jcp.32.1.66. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Jones R. N., Fuchs P. C., Barry A. L., Gavan T. L., Sommers H. M., Gerlach E. H. Cefoperazone (T-1551), a new semisynthetic cephalosporin: comparison with cephalothin and gentamicin. Antimicrob Agents Chemother. 1980 Apr;17(4):743–749. doi: 10.1128/aac.17.4.743. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Krothapalli R., Duffy W. B., Lacke C., Payne W., Patel H., Perez V., Senekjian H. O. Pseudomonas peritonitis and continuous ambulatory peritoneal dialysis. Arch Intern Med. 1982 Oct;142(10):1862–1863. [PubMed] [Google Scholar]
  14. Patrick S., Hindmarch J. M., Hague R. V., Harris D. M. Meningitis caused by Pseudomonas maltophilia. J Clin Pathol. 1975 Sep;28(9):741–743. doi: 10.1136/jcp.28.9.741. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Pedersen M. M., Marso E., Pickett M. J. Nonfermentative bacilli associated with man. 3. Pathogenicity and antibiotic susceptibility. Am J Clin Pathol. 1970 Aug;54(2):178–192. doi: 10.1093/ajcp/54.2.178. [DOI] [PubMed] [Google Scholar]
  16. Seal D. V., Strangeways J. E. Letter: Temperature-sensitivity and gentamicin-resistance in Pseudomonas aeruginosa. Lancet. 1975 Sep 13;2(7933):500–501. doi: 10.1016/s0140-6736(75)90572-3. [DOI] [PubMed] [Google Scholar]
  17. Tsuchiya K., Kondo M., Kida M., Nakao M., Iwahi T., Nishi T., Noji Y., Takeuchi M., Nozaki Y. Cefmenoxime (SCE-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities. Antimicrob Agents Chemother. 1981 Jan;19(1):56–65. doi: 10.1128/aac.19.1.56. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Yabuuchi E., Ito T., Tanimura E., Yamamoto N., Ohyama A. In vitro antimicrobial activity of ceftizoxime against glucose-nonfermentative gram-negative rods. Antimicrob Agents Chemother. 1981 Jul;20(1):136–139. doi: 10.1128/aac.20.1.136. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Zuravleff J. J., Yu V. L. Infections caused by Pseudomonas maltophilia with emphasis on bacteremia: case reports and a review of the literature. Rev Infect Dis. 1982 Nov-Dec;4(6):1236–1246. doi: 10.1093/clinids/4.6.1236. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES