Table 1.

Physicochemical characterization of conjugates.

	Lengtha,b (nm)	Primary amine loadingb,c (μmole/g S−/+)	OVA loadingb,d (mg/g S−/+) [μmol/g S−/+]	CpG loadingb,e (mg/g S−/+) [μmol/g S−/+]	αCD40 loadingb,d (mg/g S−/+) [μmol/g S−/+]
(OVA)S−/+(CpG)	122 ± 82	263 ± 72	205 ± 24 [4.5 ± 0.53]	288 ± 20 [45 ± 3.1]	–
S−/+(OVA−CpG)	122 ± 82	263 ± 72	130 ± 21 [2.9 ± 0.47]	136 ± 18 [21.2 ± 2.8]	–
(αCD40)S−/+(OVA−CpG)	122 ± 82	263 ± 72	55 ± 15 [1.2 ± 0.33]	57 ± 11 [8.8 ± 1.7]	188 ± 17 [1.3 ± 0.1]

^aDetermined from TEM images (n = 100 nanotubes).

^bData are represented as mean ± SD.

^cMeasured using TGA (n = 3).

^dMeasured using BCA assay (n = 3).

^eMeasured using NanoDrop (n = 3).