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. 1985 Nov;38(11):1258–1260. doi: 10.1136/jcp.38.11.1258

Comparison of beta enolase and myoglobin as histological markers of rhabdomyosarcoma.

J A Royds, S Variend, W R Timperley, C B Taylor
PMCID: PMC499423  PMID: 3905869

Abstract

A comparative study of beta enolase and myoglobin as markers of muscle differentiation in rhabdomyosarcoma was carried out, using an immunoperoxidase peroxidase antiperoxidase technique. Material from 26 cases of childhood rhabdomyosarcoma was studied and subdivided into embryonal and alveolar types. Positive cytoplasmic staining for beta enolase was seen in 85% of tumours studied (91% alveolar, 79% embryonal), whereas positive staining for myoglobin was detected in only 69% of tumours (82% alveolar, 64% embryonal). beta Enolase and myoglobin are useful in the histological diagnosis of rhabdomyosarcoma, and of the two, beta enolase seems to be the more sensitive.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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