Abstract
Of 30 children with bleeding disorders exposed to an index tuberculosis case, six developed primary pulmonary tuberculosis and two others became positive skin reactors. There was a significant correlation between the amount of replacement treatment received and the development of evidence of tuberculous infection. Only two of those who developed evidence of tuberculosis had antibodies to the human T cell lymphotropic virus. These two boys showed much later Mantoux positive conversion than the six others.
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Selected References
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- Beddall A. C., Hill F. G., George R. H. Haemophilia and tuberculosis. Lancet. 1983 May 28;1(8335):1226–1226. doi: 10.1016/s0140-6736(83)92510-2. [DOI] [PubMed] [Google Scholar]
- Hill J. D., Stevenson D. K. Tuberculosis in unvaccinated children, adolescents, and young adults: a city epidemic. Br Med J (Clin Res Ed) 1983 May 7;286(6376):1471–1473. doi: 10.1136/bmj.286.6376.1471. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jones J. S. A tuberculosis outbreak in Deal, Kent. Lancet. 1982 May 8;1(8280):1060–1061. doi: 10.1016/s0140-6736(82)92110-9. [DOI] [PubMed] [Google Scholar]
- Lechner K., Niessner H., Bettelheim P., Deutsch E., Fasching I., Fuhrmann M., Hinterberger W., Korninger C., Neumann E., Liszka K. T-cell alterations in hemophiliacs treated with commercial clotting factor concentrates. Thromb Haemost. 1983 Aug 30;50(2):552–556. [PubMed] [Google Scholar]
- Lederman M. M., Ratnoff O. D., Scillian J. J., Jones P. K., Schacter B. Impaired cell-mediated immunity in patients with classic hemophilia. N Engl J Med. 1983 Jan 13;308(2):79–83. doi: 10.1056/NEJM198301133080205. [DOI] [PubMed] [Google Scholar]
- Lee C. A., Janossy G., Ashley J., Kernoff P. B. Plasma fractionation methods and T-cell subsets in haemophilia. Lancet. 1983 Jul 16;2(8342):158–159. doi: 10.1016/s0140-6736(83)90136-8. [DOI] [PubMed] [Google Scholar]
- Luban N. L., Kelleher J. F., Jr, Reaman G. H. Altered distribution of T-lymphocyte subpopulations in children and adolescents with haemophilia. Lancet. 1983 Mar 5;1(8323):503–505. doi: 10.1016/s0140-6736(83)92193-1. [DOI] [PubMed] [Google Scholar]
- Menitove J. E., Aster R. H., Casper J. T., Lauer S. J., Gottschall J. L., Williams J. E., Gill J. C., Wheeler D. V., Piaskowski V., Kirchner P. T-lymphocyte subpopulations in patients with classic hemophilia treated with cryoprecipitate and lyophilized concentrates. N Engl J Med. 1983 Jan 13;308(2):83–86. doi: 10.1056/NEJM198301133080206. [DOI] [PubMed] [Google Scholar]
- Ragni M. V., Lewis J. H., Spero J. A., Bontempo F. A. Acquired-immunodeficiency-like syndrome in two haemophiliacs. Lancet. 1983 Jan 29;1(8318):213–214. doi: 10.1016/s0140-6736(83)92589-8. [DOI] [PubMed] [Google Scholar]
- Smith W. H., Davies D., Mason K. D., Onions J. P. Intraoral and pulmonary tuberculosis following dental treatment. Lancet. 1982 Apr 10;1(8276):842–844. doi: 10.1016/s0140-6736(82)91886-4. [DOI] [PubMed] [Google Scholar]