Abstract
Adenocarcinoma of the anal glands is very rare but it is an important lesion to recognise as with early diagnosis, it has an excellent prognosis. Because it involves the submucosa widely and penetrates the mucosa late, it can be mistaken for metastatic gastrointestinal carcinoma, or tumour arising in sinuses and fistulae. Two cases, in a 44 year old man and a 73 year old woman, which illustrate the typical features are reported, in one of which the diagnosis was missed originally. In situ neoplastic change of the associated anal glands and secretion of mucin lacking O-acetyl groups are useful pointers.
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- Abel M. E., Chiu Y. S., Russell T. R., Volpe P. A. Adenocarcinoma of the anal glands. Results of a survey. Dis Colon Rectum. 1993 Apr;36(4):383–387. doi: 10.1007/BF02053944. [DOI] [PubMed] [Google Scholar]
- Fenger C., Filipe M. I. Mucin histochemistry of the anal canal epithelium. Studies of normal anal mucosa and mucosa adjacent to carcinoma. Histochem J. 1981 Nov;13(6):921–930. doi: 10.1007/BF01002632. [DOI] [PubMed] [Google Scholar]
- GRINVALSKY H. T., HELWIG E. B. Carcinoma of the anorectal junction. I. Histological considerations. Cancer. 1956 May-Jun;9(3):480–488. doi: 10.1002/1097-0142(195605/06)9:3<480::aid-cncr2820090309>3.0.co;2-6. [DOI] [PubMed] [Google Scholar]
- Tarazi R., Nelson R. L. Anal adenocarcinoma: a comprehensive review. Semin Surg Oncol. 1994 May-Jun;10(3):235–240. doi: 10.1002/ssu.2980100312. [DOI] [PubMed] [Google Scholar]
- WELLMAN K. F. Adenocarcinoma of anal duct origin. Can J Surg. 1962 Jul;5:311–318. [PubMed] [Google Scholar]
- WINKELMAN J., GROSFELD J., BIGELOW B. COLLOID CARCINOMA OF ANAL-GLAND ORIGIN. REPORT OF A CASE AND REVIEW OF THE LITERATURE. Am J Clin Pathol. 1964 Oct;42:395–401. doi: 10.1093/ajcp/42.4.395. [DOI] [PubMed] [Google Scholar]