Abstract
A murine monoclonal antibody, which recognises various serotypes of group B Streptococcus in formalin fixed, paraffin embedded tissue, was used to show the organism in necropsy specimens of newborn infant lung by an indirect immunoperoxidase technique. The method seemed to be complementary to that of Gram staining, and may be successfully used to identify group B Streptococcus antigen in histopathological material.
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- Doran T. I., Straus D. C., Mattingly S. J. Extracellular antigens of serotype III group B streptococci. Infect Immun. 1980 Dec;30(3):890–893. doi: 10.1128/iai.30.3.890-893.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Friedman C. A., Wender D. F., Rawson J. E. Rapid diagnosis of group B streptococcal infection utilizing a commercially available latex agglutination assay. Pediatrics. 1984 Jan;73(1):27–30. [PubMed] [Google Scholar]
- Köhler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975 Aug 7;256(5517):495–497. doi: 10.1038/256495a0. [DOI] [PubMed] [Google Scholar]
- Lancefield R. C., McCarty M., Everly W. N. Multiple mouse-protective antibodies directed against group B streptococci. Special reference to antibodies effective against protein antigens. J Exp Med. 1975 Jul 1;142(1):165–179. doi: 10.1084/jem.142.1.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lannering B., Larsson L. E., Rojas J., Stahlman M. T. Early onset group B streptococcal disease. Seven year experience and clinical scoring system. Acta Paediatr Scand. 1983 Jul;72(4):597–602. doi: 10.1111/j.1651-2227.1983.tb09777.x. [DOI] [PubMed] [Google Scholar]
- Leland D. S., Lachapelle R. C., Wlodarski F. M. Method for rapid detection of group B streptococci by coagglutination. J Clin Microbiol. 1978 Apr;7(4):323–326. doi: 10.1128/jcm.7.4.323-326.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mepham B. L., Frater W., Mitchell B. S. The use of proteolytic enzymes to improve immunoglobulin staining by the PAP technique. Histochem J. 1979 May;11(3):345–357. doi: 10.1007/BF01005033. [DOI] [PubMed] [Google Scholar]
- Morrow D. L., Kline J. B., Douglas S. D., Polin R. A. Rapid detection of group B streptococcal antigen by monoclonal antibody sandwich enzyme assay. J Clin Microbiol. 1984 Apr;19(4):457–459. doi: 10.1128/jcm.19.4.457-459.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ridley M. J., Ridley D. S. The immunopathology of erythema nodosum leprosum: the role of extravascular complexes. Lepr Rev. 1983 Jun;54(2):95–107. doi: 10.5935/0305-7518.19830015. [DOI] [PubMed] [Google Scholar]
- Riser E., Noone P., Poulton T. A. A new serotyping method for Klebsiella species: development of the technique. J Clin Pathol. 1976 Apr;29(4):296–304. doi: 10.1136/jcp.29.4.296. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ruch F. E., Jr, Smith L. Monoclonal antibody to streptococcal group B carbohydrate: applications in latex agglutination and immunoprecipitin assays. J Clin Microbiol. 1982 Jul;16(1):145–152. doi: 10.1128/jcm.16.1.145-152.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stein H., Bonk A., Tolksdorf G., Lennert K., Rodt H., Gerdes J. Immunohistologic analysis of the organization of normal lymphoid tissue and non-Hodgkin's lymphomas. J Histochem Cytochem. 1980 Aug;28(8):746–760. doi: 10.1177/28.8.7003001. [DOI] [PubMed] [Google Scholar]


