Table 2.
Periods Groups | Body Weights (g) | Body Weight Gains During Treatment (g) | ||
---|---|---|---|---|
At OVX a | At Initial Treatment a | At Sacrifice a | ||
Controls | ||||
Sham | 23.61 ± 1.64 | 24.75 ± 1.81 | 28.00 ± 2.23 | 3.25 ± 1.92 |
OVX | 24.21 ± 1.47 | 30.78 ± 2.12 * | 42.90 ± 2.28 * | 14.68 ± 2.88 * |
Estradiol | 24.65 ± 0.99 | 28.71 ± 1.61 * | 35.68 ± 2.19 *,# | 6.96 ± 1.21 *,# |
RC | 23.93 ± 1.47 | 28.98 ± 1.73 * | 36.44 ± 1.52 *,# | 8.15 ± 0.95 *,# |
PCP | 24.60 ± 1.19 | 28.78 ± 2.02 * | 37.30 ± 2.38 *,# | 8.53 ± 1.31 *,# |
RC:PCP | ||||
1:1 | 24.41 ± 0.97 | 28.53 ± 1.65 * | 33.26 ± 1.85 *,#,†,‡ | 4.74 ± 1.55 #,†,‡ |
1:2 | 24.69 ± 1.33 | 28.56 ± 1.78 * | 35.24 ± 2.54 *,# | 6.68 ± 2.55 *,# |
1:4 | 24.40 ± 0.97 | 28.44 ± 1.52 * | 35.59 ± 2.05 *,# | 7.15 ± 1.86 *,# |
1:8 | 24.66 ± 1.11 | 28.69 ± 1.31 * | 35.69 ± 1.95 *,# | 7.00 ± 2.58 *,# |
2:1 | 24.58 ± 1.08 | 28.50 ± 1.54 * | 32.29 ± 2.53 *,#,†,‡ | 3.79 ± 2.28 #,†,‡ |
4:1 | 24.31 ± 1.86 | 28.41 ± 0.88 * | 33.64 ± 1.45 *,#,†,‡ | 5.23 ± 1.80 #,†,‡ |
8:1 | 24.61 ± 1.77 | 28.73 ± 1.12 * | 36.86 ± 4.74 *,# | 8.14 ± 4.99 *,# |
Values are expressed mean ± S.D. of eight mice. a All animals were overnight fasted; * p < 0.01 as compared with sham control; # p < 0.05 as compared with OVX control; † p < 0.05 as compared with RC single formula treated mice; ‡ p < 0.01 as compared with PCP single formula treated mice; OVX = Bilateral ovariectomy; RC = Red clover dry extracts; PCP = Pomegranate Concentrate Powder; RC:PCP = Mixed formulations consisted of RC and PCP (g/g).