Table 5.
Histopathology-Histomorphometry for the uterus in sham-operated or OVX ddY mice.
| Items Groups | Left Uterine Horn Tissues | |||
|---|---|---|---|---|
| Total Thickness (μm) | Epithelium Thickness (μm) | Mucosa Layer Thickness (μm) | Uterine Gland Regions (%) | |
| Controls | ||||
| Sham | 2177.82 ± 573.19 | 34.58 ± 6.17 | 951.22 ± 242.86 | 53.94 ± 12.02 |
| OVX | 566.47 ± 128.78 * | 7.68 ± 1.26 * | 202.25 ± 46.58 * | 12.46 ± 3.07 * |
| Estradiol | 1593.32 ± 371.85 *,# | 20.75 ± 4.52 *,# | 598.74 ± 153.51 *,# | 34.93 ± 4.60 *,# |
| RC | 776.35 ± 97.07 *,# | 11.62 ± 3.02 *,# | 295.40 ± 45.06 *,# | 24.03 ± 6.13 *,# |
| PCP | 739.04 ± 84.66 *,# | 11.06 ± 2.72 *,# | 282.10 ± 37.26 *,# | 22.47 ± 4.28 *,# |
| RC:PCP | ||||
| 1:1 | 1003.98 ± 173.11 *,#,†,‡ | 17.96 ± 4.26 *,#,†,‡ | 409.30 ± 31.93 *,#,†,‡ | 32.91 ± 3.70 *,#,†,‡ |
| 1:2 | 789.85 ± 116.09 *,# | 13.16 ± 4.17 *,# | 314.95 ± 79.42 *,# | 26.10 ± 6.70 *,# |
| 1:4 | 776.76 ± 98.02 *,# | 12.46 ± 3.50 *,# | 297.63 ± 45.24 *,# | 23.88 ± 3.85 *,# |
| 1:8 | 746.54 ± 64.96 *,# | 11.22 ± 2.41 *,# | 285.57 ± 40.39 *,# | 22.54 ± 4.56 *,# |
| 2:1 | 1124.93 ± 125.59 *,#,†,‡ | 23.46 ± 4.93 *,#,†,‡ | 455.64 ± 92.39 *,#,†,‡ | 35.65 ± 6.07 *,#,†,‡ |
| 4:1 | 917.42 ± 54.64 *,#,†,‡ | 16.87 ± 4.11 *,#,†,‡ | 372.29 ± 44.26 *,#,†,‡ | 32.37 ± 4.67 *,#,†,‡ |
| 8:1 | 796.67 ± 146.28 *,# | 12.11 ± 3.99 *,# | 309.44 ± 44.82 *,# | 24.71 ± 4.22 *,# |
Values are expressed mean ± S.D. of eight mice. * p < 0.05 as compared with sham control; # p < 0.05 as compared with OVX control; † p < 0.05 as compared with RC single formula treated mice; ‡ p < 0.01 as compared with PCP single formula treated mice. OVX = Bilateral ovariectomy; RC = Red clover dry extracts; PCP = Pomegranate Concentrate Powder; RC:PCP = Mixed formulations consisted of RC and PCP (g/g).