Abstract
The possibility that the small intestine may represent a reservoir for Clostridium difficile was studied, using segments of human jejunum collected at necropsy. Our results (three of 100 specimens positive for C difficile culture) support the hypothesis that C difficile can be found in human jejunum and that it adheres to the normal mucosa as a resident bacterium. These findings suggest that gastrointestinal disease caused by C difficile has an endogenous origin.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- George W. L., Sutter V. L., Citron D., Finegold S. M. Selective and differential medium for isolation of Clostridium difficile. J Clin Microbiol. 1979 Feb;9(2):214–219. doi: 10.1128/jcm.9.2.214-219.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Malamou-Ladas H., O'Farrell S., Nash J. Q., Tabaqchali S. Isolation of Clostridium difficile from patients and the environment of hospital wards. J Clin Pathol. 1983 Jan;36(1):88–92. doi: 10.1136/jcp.36.1.88. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mulligan M. E., George W. L., Rolfe R. D., Finegold S. M. Epidemiological aspects of Clostridium difficile-induced diarrhea and colitis. Am J Clin Nutr. 1980 Nov;33(11 Suppl):2533–2538. doi: 10.1093/ajcn/33.11.2533. [DOI] [PubMed] [Google Scholar]
- Taylor R. H., Borriello S. P., Taylor A. J. Isolation of Clostridium difficile from the small bowel. Br Med J (Clin Res Ed) 1981 Aug 8;283(6288):412–412. doi: 10.1136/bmj.283.6288.412. [DOI] [PMC free article] [PubMed] [Google Scholar]