Table 2.

Structural connectivity values for the three groups

Connections	Structural connectivity (mean ± SD)			Corrected p value
	NC	SWEDD	PD	PD-NC	SWEDD-NC	SWEDD-PD
Associative cortex–caudate	0.671 ± 1.381	0.299 ± 0.453	0.232 ± 0.319	0.017	0.054	0.214
Associative cortex–putamen	3.452 ± 1.561	3.471 ± 1.517	3.734 ± 1.771	0.228	0.487	0.232
Associative cortex–thalamus	0.833 ± 0.488	0.650 ± 0.367	1.173 ± 0.750	0.009	0.032	<0.001
Limbic cortex–caudate	2.197 ± 1.463	1.902 ± 1.310	0.710 ± 1.215	<0.001	0.162	<0.001
Limbic cortex–putamen	3.175 ± 1.272	3.271 ± 1.474	2.557 ± 1.147	0.013	0.387	0.008
Limbic cortex–thalamus	1.535 ± 0.810	1.379 ± 0.866	1.054 ± 0.889	0.005	0.194	0.048
Sensorimotor cortex–caudate	0.430 ± 0.993	0.170 ± 0.471	0.053 ± 0.076	<0.001	0.062	0.016
Sensorimotor cortex–putamen	1.250 ± 0.742	1.485 ± 0.930	1.728 ± 1.108	0.011	0.010	0.027
Sensorimotor cortex–thalamus	0.964 ± 0.574	0.947 ± 0.537	1.019 ± 0.703	0.325	0.511	0.292
Pallidum–caudate	0.676 ± 0.644	0.838 ± 0.744	0.631 ± 0.825	0.374	0.145	0.112
Pallidum–putamen	2.166 ± 0.898	1.840 ± 0.917	1.283 ± 0.522	<0.001	0.045	<0.001
Pallidum–thalamus	0.799 ± 0.519	0.926 ± 0.523	0.565 ± 0.452	0.007	0.143	<0.001
Putamen–thalamus	0.439 ± 0.437	0.477 ± 0.388	0.346 ± 0.298	0.132	0.295	0.044
Substantia nigra–putamen	0.004 ± 0.017	0.001 ± 0.004	0.004 ± 0.015	0.496	0.179	0.192
Substantia nigra–thalamus	0.001 ± 0.005	0.004 ± 0.012	0.009 ± 0.003	0.193	0.045	0.223
Substantia nigra–pallidum	0.096 ± 0.243	0.095 ± 0.363	0.160 ± 0.129	0.210	0.485	0.350

Structural connectivity values based on fiber density were reported for 16 connections within the CBGT circuit. The values were reported as the mean ± standard deviation (SD). Group-wise differences in NC-PD, SWEDD-NC and SWEDD-PD comparisons were reported using corrected p values. The italicised text shows identified connections with significant differences among the three comparisons