Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1997 Oct;50(10):869–870. doi: 10.1136/jcp.50.10.869

Epithelioid sarcoma of the tongue.

X Leroy 1, A Delobelle 1, J L Lefebvre 1, V Cabaret 1, F Bloget 1, M O Vilain 1
PMCID: PMC500273  PMID: 9462274

Abstract

A case of epithelioid sarcoma in the tongue is reported. The patient, a 35 year old woman, presented with a non-ulcerated painful lesion of the tongue. Microscopically, the tumour was characterised by multiple coalescent nodules with central geographic necrosis infiltrating the lingual muscle. The tumour cells were epithelioid with abundant eosinophilic cytoplasm and atypical nuclei. Immunohistochemically, the tumour cells stained for vimentin, keratin, and epithelial membrane antigen. These morphological and immunohistochemical appearances led to the diagnosis of epithelioid sarcoma of the tongue. Seven years later, the patient died with metastatic dissemination to the scalp, lungs, and brain. No case of epithelioid sarcoma arising in the tongue has been described previously.

Full text

PDF
869

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arber D. A., Kandalaft P. L., Mehta P., Battifora H. Vimentin-negative epithelioid sarcoma. The value of an immunohistochemical panel that includes CD34. Am J Surg Pathol. 1993 Mar;17(3):302–307. [PubMed] [Google Scholar]
  2. Chetty R., Slavin J. L. Epithelioid sarcoma with extensive chondroid differentiation. Histopathology. 1994 Apr;24(4):400–401. doi: 10.1111/j.1365-2559.1994.tb00547.x. [DOI] [PubMed] [Google Scholar]
  3. Enzinger F. M. Epitheloid sarcoma. A sarcoma simulating a granuloma or a carcinoma. Cancer. 1970 Nov;26(5):1029–1041. doi: 10.1002/1097-0142(197011)26:5<1029::aid-cncr2820260510>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
  4. Halling A. C., Wollan P. C., Pritchard D. J., Vlasak R., Nascimento A. G. Epithelioid sarcoma: a clinicopathologic review of 55 cases. Mayo Clin Proc. 1996 Jul;71(7):636–642. doi: 10.1016/S0025-6196(11)63000-0. [DOI] [PubMed] [Google Scholar]
  5. Jameson C. F., Simpson M. T., Towers J. F. Primary epithelioid sarcoma of the hard palate. A case report. Int J Oral Maxillofac Surg. 1990 Aug;19(4):240–242. doi: 10.1016/s0901-5027(05)80401-1. [DOI] [PubMed] [Google Scholar]
  6. Manivel J. C., Wick M. R., Dehner L. P., Sibley R. K. Epithelioid sarcoma. An immunohistochemical study. Am J Clin Pathol. 1987 Mar;87(3):319–326. doi: 10.1093/ajcp/87.3.319. [DOI] [PubMed] [Google Scholar]
  7. Mirra J. M., Kessler S., Bhuta S., Eckardt J. The fibroma-like variant of epithelioid sarcoma. A fibrohistiocytic/myoid cell lesion often confused with benign and malignant spindle cell tumors. Cancer. 1992 Mar 15;69(6):1382–1395. doi: 10.1002/1097-0142(19920315)69:6<1382::aid-cncr2820690614>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
  8. Molenaar W. M., DeJong B., Dam-Meiring A., Postma A., DeVries J., Hoekstra H. J. Epithelioid sarcoma or malignant rhabdoid tumor of soft tissue? Epithelioid immunophenotype and rhabdoid karyotype. Hum Pathol. 1989 Apr;20(4):347–351. doi: 10.1016/0046-8177(89)90044-0. [DOI] [PubMed] [Google Scholar]
  9. von Hochstetter A. R., Meyer V. E., Grant J. W., Honegger H. P., Schreiber A. Epithelioid sarcoma mimicking angiosarcoma: the value of immunohistochemistry in the differential diagnosis. Virchows Arch A Pathol Anat Histopathol. 1991;418(3):271–278. doi: 10.1007/BF01606067. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES