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. 1996 Mar;49(3):255–257. doi: 10.1136/jcp.49.3.255

Microbiological and serological investigations of oral lesions in Papillon-Lefèvre syndrome.

V Clerehugh 1, D B Drucker 1, G J Seymour 1, P S Bird 1
PMCID: PMC500410  PMID: 8675741

Abstract

Microbiological and serological (enzyme linked immunosorbent assay) investigations were carried out, including karyotyping, on two Asian children with Papillon-Lefèvre syndrome. In case 1, a girl aged four years, the most prevalent putative periodontopathogens were Eikenella corrodens, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella intermedia (deciduous dentition) and Bacteroides gracilis, E corrodens and F nucleatum (permanent dentition). In case 2, a boy aged nine years, they were F nucleatum, P intermedia and P loeschii and E corrodens. Serum from case 2 showed a raised specific IgG antibody response to Actinomyces actino-mycetemcomitans serotype b. Thus, a wider range of species than hitherto reported may be associated with Papillon-Lefèvre syndrome, including A actino-mycetemcomitans and F nucleatum.

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Selected References

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