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Xenologous engraftment of juvenile myelomonocytic leukemia (JMML) cells in Rag2−/−γc−/− mice results in decreased survival. Of 58 mice with xenologous JMML cell engraftment after transplantation, 39 were sacrificed at elected time points (not included in this Figure) and 19 were informative for survival analysis (solid line). Survival of non-transplanted control mice was unaffected (dotted line, n=5) (P=0.0004, Mantel-Cox log rank test).
