Abstract
Non-Hodgkin's lymphoma is not commonly a familial condition. This is believed to be the first two cases of primary pancreatic lymphoma within a single family. The two cases, a brother and sister, both presented in their 60s and were diagnosed histologically as having high grade B cell lymphoma affecting the pancreas, an uncommon primary site. Both responded well to treatment with chemotherapy and were in remission at the time of writing. On further investigation it was found that their mother also presented with a malignant lymphoma of cervical nodes 30 years earlier and subsequently died of the disease.
Full text
PDF


Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cartwright R. A., McKinney P. A., O'Brien C., Richards I. D., Roberts B., Lauder I., Darwin C. M., Bernard S. M., Bird C. C. Non-Hodgkin's lymphoma: case control epidemiological study in Yorkshire. Leuk Res. 1988;12(1):81–88. doi: 10.1016/s0145-2126(98)80012-x. [DOI] [PubMed] [Google Scholar]
- Haim N., Cohen Y., Robinson E. Malignant lymphoma in first-degree blood relatives. Cancer. 1982 May 15;49(10):2197–2200. doi: 10.1002/1097-0142(19820515)49:10<2197::aid-cncr2820491036>3.0.co;2-9. [DOI] [PubMed] [Google Scholar]
- Harris N. L., Jaffe E. S., Stein H., Banks P. M., Chan J. K., Cleary M. L., Delsol G., De Wolf-Peeters C., Falini B., Gatter K. C. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood. 1994 Sep 1;84(5):1361–1392. [PubMed] [Google Scholar]
- Hart M. J., White T. T., Brown P. C., Freeny P. C. Potentially curable masses in the pancreas. Am J Surg. 1987 Jul;154(1):134–136. doi: 10.1016/0002-9610(87)90303-5. [DOI] [PubMed] [Google Scholar]
- Linet M. S., Pottern L. M. Familial aggregation of hematopoietic malignancies and risk of non-Hodgkin's lymphoma. Cancer Res. 1992 Oct 1;52(19 Suppl):5468s–5473s. [PubMed] [Google Scholar]
- Webb T. H., Lillemoe K. D., Pitt H. A., Jones R. J., Cameron J. L. Pancreatic lymphoma. Is surgery mandatory for diagnosis or treatment? Ann Surg. 1989 Jan;209(1):25–30. doi: 10.1097/00000658-198901000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]


