Abstract
Delay in reporting the immunofluorescence findings on renal biopsies, owing to an interruption in supply of reagents, made possible a retrospective analysis of the effect of the lack of this information on patient management. Hospital case records of the 39 patients so affected were reviewed to determine what changes in their management took place after the immunofluorescence findings became available. The clinical, laboratory, and light microscopic findings in all except a case of pauci-immune crescentic glomerulonephritis allowed management decisions to be made that were not influenced by immunofluorescence findings. This was owing to correct prediction of the immunofluorescence findings, as in cases of IgA nephropathy presenting with recurrent haematuria; the adequacy of light microscopy in the interpretation of graft biopsies, in classifying lupus nephritis and in most cases of nephrotic syndrome; and the absence of entities identifiable only by immunofluorescence among these patients.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Date A., Pant M. How useful is immunofluorescence in tropical renal pathology? Trans R Soc Trop Med Hyg. 1990 Jul-Aug;84(4):599–601. doi: 10.1016/0035-9203(90)90055-j. [DOI] [PubMed] [Google Scholar]
- Date A., Raghavan R., John T. J., Richard J., Kirubakaran M. G., Shastry J. C. Renal disease in adult Indians: a clinicopathological study of 2,827 patients. Q J Med. 1987 Sep;64(245):729–737. [PubMed] [Google Scholar]
- Date A., Unni J. C., Raghupathy P., Jadhav M., Pereira S. M., Richard J., Jacob C. K., Kirubakaran M. G., Shastry J. C. The pattern of medical renal disease in children in a south Indian hospital. Ann Trop Paediatr. 1984 Dec;4(4):207–211. doi: 10.1080/02724936.1984.11748336. [DOI] [PubMed] [Google Scholar]