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. 2016 Mar 28;5(7):e1164918. doi: 10.1080/2162402X.2016.1164918

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 4. — Transcriptome analysis of enriched splenic CD11c⁺ cells. (A) Heatmap of differentially expressed genes considering a p value of <0.05 as significantly changed. (B) Selection of most significantly changed Kegg pathways containing differentially expressed genes in splenic CD11c⁺ cells from myPTEN^−/− and myPTEN^+/+ mice; list is sorted according to p value. (C) Fold changes of transcription factors involved in DC development and function. (D) Fold changes of selected genes know to be differentially regulated between myPTEN^−/− and myPTEN^+/+ in CD11b⁺ and CD11c⁺ cells.