Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1998 Nov;51(11):846–849. doi: 10.1136/jcp.51.11.846

How to improve low lymph node recovery rates from axillary clearance specimens of breast cancer. A short-term audit.

G Cserni 1
PMCID: PMC500980  PMID: 10193327

Abstract

AIM: To implement an audit scheme to increase the lymph node yield from axillary clearance specimens. METHODS: Two pathologists cut up each specimen after weighing it. The number of nodes and the dimensions of the largest and smallest nodes were recorded, together with the number of non-lymph node structures recovered. Fifty consecutive audited cases were compared with 50 consecutive cases assessed before the audit process. RESULTS: It proved possible to increase the median number of lymph nodes from 10 to 22. There was an obvious learning period, during which the number of nodes recovered during the second pathologist's cut-up gradually decreased, while the total number remained relatively constant. The increase in lymph node yield resulted from the recovery of smaller nodes. The identification of lymph nodes also improved, and fewer non-lymph node structures were recovered by the end of the study. CONCLUSIONS: Such an audit scheme can be recommended for all institutions where the lymph node yield of axillary clearance specimens seems suboptimal. The relevance of recovering more nodes remains to be determined; from this small series, it seems to have no clinical impact.

Full text

PDF
846

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blichert-Toft M., Smola M. G., Cataliotti L., O'Higgins N. Principles and guidelines for surgeons--management of symptomatic breast cancer. European Society of Surgical Oncology. Eur J Surg Oncol. 1997 Apr;23(2):101–109. doi: 10.1016/s0748-7983(97)80001-7. [DOI] [PubMed] [Google Scholar]
  2. Cady B. Total mastectomy and partial axillary dissection. Surg Clin North Am. 1973 Apr;53(2):313–318. doi: 10.1016/s0039-6109(16)39983-2. [DOI] [PubMed] [Google Scholar]
  3. Fisher B., Slack N. H. Number of lymph nodes examined and the prognosis of breast carcinoma. Surg Gynecol Obstet. 1970 Jul;131(1):79–88. [PubMed] [Google Scholar]
  4. Fisher B., Wolmark N., Bauer M., Redmond C., Gebhardt M. The accuracy of clinical nodal staging and of limited axillary dissection as a determinant of histologic nodal status in carcinoma of the breast. Surg Gynecol Obstet. 1981 Jun;152(6):765–772. [PubMed] [Google Scholar]
  5. Kiricuta C. I., Tausch J. A mathematical model of axillary lymph node involvement based on 1446 complete axillary dissections in patients with breast carcinoma. Cancer. 1992 May 15;69(10):2496–2501. doi: 10.1002/1097-0142(19920515)69:10<2496::aid-cncr2820691018>3.0.co;2-t. [DOI] [PubMed] [Google Scholar]
  6. Kirkham N., Cotton D. W. Measuring melanomas: the Vernier method. J Clin Pathol. 1984 Feb;37(2):229–230. doi: 10.1136/jcp.37.2.229. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kjaergaard J., Blichert-Toft M., Andersen J. A., Rank F., Pedersen B. V. Probability of false negative nodal staging in conjunction with partial axillary dissection in breast cancer. Br J Surg. 1985 May;72(5):365–367. doi: 10.1002/bjs.1800720511. [DOI] [PubMed] [Google Scholar]
  8. Mathiesen O., Carl J., Bonderup O., Panduro J. Axillary sampling and the risk of erroneous staging of breast cancer. An analysis of 960 consecutive patients. Acta Oncol. 1990;29(6):721–725. doi: 10.3109/02841869009092990. [DOI] [PubMed] [Google Scholar]
  9. Reynolds J. V., Mercer P., McDermott E. W., Cross S., Stokes M., Murphy D., O'Higgins N. J. Audit of complete axillary dissection in early breast cancer. Eur J Cancer. 1994;30A(2):148–149. doi: 10.1016/0959-8049(94)90075-2. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES