Abstract
A 39 year old female presented with bilateral pneumothoraces and interstitial shadowing on chest x ray. A diagnosis of lymphangioleiomyomatosis was made following an open lung biopsy. Over the next eight years she developed respiratory failure leading to single lung transplantation but she died in the immediate postoperative period. Necropsy examination and review of the previous open lung biopsy revealed multiple pulmonary metastases from a low grade endometrial stromal sarcoma of the uterus. This case high-lights the importance of an accurate diagnosis before transplantation.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Aaro L. A., Symmonds R. E., Dockerty M. B. Sarcoma of the uterus. A clinical and pathologic study of 177 cases. Am J Obstet Gynecol. 1966 Jan 1;94(1):101–109. doi: 10.1016/0002-9378(66)90386-3. [DOI] [PubMed] [Google Scholar]
- Abrams J., Talcott J., Corson J. M. Pulmonary metastases in patients with low-grade endometrial stromal sarcoma. Clinicopathologic findings with immunohistochemical characterization. Am J Surg Pathol. 1989 Feb;13(2):133–140. doi: 10.1097/00000478-198902000-00006. [DOI] [PubMed] [Google Scholar]
- Bonetti F., Chiodera P. L., Pea M., Martignoni G., Bosi F., Zamboni G., Mariuzzi G. M. Transbronchial biopsy in lymphangiomyomatosis of the lung. HMB45 for diagnosis. Am J Surg Pathol. 1993 Nov;17(11):1092–1102. doi: 10.1097/00000478-199311000-00002. [DOI] [PubMed] [Google Scholar]
- Dormans T. P., Verrips A., Bulten J., Cox N. Pulmonary lymphangioleiomyomatosis and cerebrotendinous xanthomatosis: is there a link? Chest. 1997 Jul;112(1):273–274. doi: 10.1378/chest.112.1.273. [DOI] [PubMed] [Google Scholar]
- Flint A., Lynch J. P., 3rd, Martinez F. J., Whyte R. I. Pulmonary smooth muscle proliferation occurring after lung transplantation. Chest. 1997 Jul;112(1):283–284. doi: 10.1378/chest.112.1.283. [DOI] [PubMed] [Google Scholar]
- KOSS L. G., SPIRO R. H., BRUNSCHWIG A. ENDOMETRIAL STROMAL SARCOMA. Surg Gynecol Obstet. 1965 Sep;121:531–537. [PubMed] [Google Scholar]
- Stewart S. Pathology of lung transplantation. Semin Diagn Pathol. 1992 Aug;9(3):210–219. [PubMed] [Google Scholar]