Figure 1.

Metabolic signatures of cRets and nRets are similar. Metabolomes of cRets from blood from 4 independent umbilical cords and nRets from 5 independent umbilical cords were analyzed by LC/MS followed by identification in the metabolite database.⁵ A diagram of high- and low-expressed metabolites is shown. cRets data are expressed as log₂ fold relative to the average expression level in nRets for each metabolite. Metabolites expression was considered significantly different between cRets and nRets when log₂R was above +2 or below −2 (black bars) and was considered identical when log₂R was between +2 and −2 (gray bars). Statistical significance was assessed with a Mann-Whitney test: ns: not significant; *P≤ 0.05. ФThis value has been arbitrarily set at 0 (−∞ as a log₂0) for ease of display.