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. 2016 Jan 25;5(3):275–282. doi: 10.1080/21623945.2015.1134402

Figure 5.

Figure 5.

Murine adipocytes from obese, but not lean mice, induce IL-17A secretion in MNC-adipocytes co-cultures. Adipocytes from subcutaneous adipose tissue of mice fed a standard diet (SD, gray bars) or a high-fat diet (HFD, black bars) were co-incubated with spleen-derived MNC and stimulated or not with PHA. Cell culture supernatants were analyzed by ELISA for the secretion of murine IL-17A. Error bars represent standard deviations from n ≥ 5 independent experiments. ***p < 0.001; as tested by one-way ANOVA followed by Bonferroni's multiple comparison test. n.s not statistically significant.