Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1999 Nov;52(11):849–850. doi: 10.1136/jcp.52.11.849

CD10 positive thyroid marginal zone non-Hodgkin lymphoma.

E K Millar 1, S Waldron 1, A Spencer 1, S Braye 1
PMCID: PMC501601  PMID: 10690178

Abstract

A 72 year old woman presented with swelling of the right lobe of her thyroid gland. Fine needle aspiration and flow cytometry showed a clonal population of B cells expressing CD10 and a diagnosis of follicle centre cell lymphoma was made. Subsequent excision of the thyroid showed the typical histological features of a marginal zone non-Hodgkin lymphoma. Polymerase chain reaction showed no evidence of t (14;18). Immunohistochemistry confirmed CD10 positivity and LN1 (CDw75) expression. This is only the second report of aberrant expression of CD 10 by a marginal zone lymphoma.

Full text

PDF
849

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ballesteros E., Osborne B. M., Matsushima A. Y. CD5+ low-grade marginal zone B-cell lymphomas with localized presentation. Am J Surg Pathol. 1998 Feb;22(2):201–207. doi: 10.1097/00000478-199802000-00008. [DOI] [PubMed] [Google Scholar]
  2. Isaacson P. G. Malignant lymphomas with a follicular growth pattern. Histopathology. 1996 Jun;28(6):487–495. doi: 10.1046/j.1365-2559.1996.d01-473.x. [DOI] [PubMed] [Google Scholar]
  3. Phillips A. J., Tomasec P., Wang E. C., Wilkinson G. W., Borysiewicz L. K. Human cytomegalovirus infection downregulates expression of the cellular aminopeptidases CD10 and CD13. Virology. 1998 Oct 25;250(2):350–358. doi: 10.1006/viro.1998.9385. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES