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. 1989 Nov;42(11):1157–1159. doi: 10.1136/jcp.42.11.1157

Umbilical cord sclerosis as an indicator of congenital syphilis.

S Knowles 1, T Frost 1
PMCID: PMC501973  PMID: 2584428

Abstract

In two cases of congenital syphilis examination of the umbilical cord showed a distinctive picture of perivascular sclerosis and inflammation. Large numbers of spirochaetes were shown in the sclerotic zone in both cases. No organisms were demonstrable in the placental disc and there were no morphological changes suggestive of syphilis. It is concluded that the finding of sclerosing funisitis, together with the clinical circumstances, should raise the possibility of congenital syphilis.

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Selected References

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  1. Malpas P. A case of constrictive sclerosis of Wharton's jelly associated with detachment of the placenta. J Obstet Gynaecol Br Commonw. 1968 Jun;75(6):678–679. doi: 10.1111/j.1471-0528.1968.tb00180.x. [DOI] [PubMed] [Google Scholar]
  2. Overbach A. M., Daniel S. J., Cassady G. The value of umbilical cord histology in the management of potential perinatal infection. J Pediatr. 1970 Jan;76(1):22–31. doi: 10.1016/s0022-3476(70)80125-1. [DOI] [PubMed] [Google Scholar]
  3. Russell P., Altshuler G. Placental abnormalities of congenital syphilis. A neglected aid to diagnosis. Am J Dis Child. 1974 Aug;128(2):160–163. doi: 10.1001/archpedi.1974.02110270034007. [DOI] [PubMed] [Google Scholar]
  4. WILSON M. G., ARMSTRONG D. H. INFLAMMATION OF THE UMBILICAL CORD AND NEONATAL ILLNESS. Am J Obstet Gynecol. 1964 Dec 1;90:843–849. doi: 10.1016/0002-9378(64)90775-6. [DOI] [PubMed] [Google Scholar]

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