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. 1989 Nov;42(11):1215–1221. doi: 10.1136/jcp.42.11.1215

Comparison of immunodiffusion and enzyme linked immunosorbent assay for antibodies to four Aspergillus species.

J H Froudist 1, G B Harnett 1, R McAleer 1
PMCID: PMC501985  PMID: 2511230

Abstract

Antigenic extracts were prepared from Aspergillus fumigatus, A niger, A flavus and A terreus for use in enzyme linked immunosorbent assay (ELISA) and immunodiffusion (ID) tests for Aspergillus antibodies to determine whether the use of antigenic extracts from species other than A fumigatus increased the sensitivity of the ELISA. ELISA titres correlated well with positive ID tests. Patient titres by ELISA were significantly higher than control titres for all species. Patient titres to A niger were also significantly higher than titres to the other species. Total number of ID bands to A fumigatus correlated significantly with anti-A fumigatus ELISA titres. It is concluded that the use of antigenic extracts from species other than A fumigatus improves the sensitivity of the ELISA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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