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Infectious Diseases and Therapy logoLink to Infectious Diseases and Therapy
. 2016 Aug 26;5(3):363–365. doi: 10.1007/s40121-016-0127-9

Erratum to: Single-Dose Oritavancin Treatment of Acute Bacterial Skin and Skin Structure Infections: SOLO Trial Efficacy by Eron Severity and Management Setting

Daniel H Deck 1,, Jennifer M Jordan 1,, Thomas L Holland 2, Weihong Fan 1, Matthew A Wikler 1, Katherine A Sulham 1, G Ralph Corey 2
PMCID: PMC5019983  PMID: 27565805

Erratum to: Infect Dis Ther (2016) DOI 10.1007/s40121-016-0119-9

Following publication of the aforementioned article, the authors noted a minor error in Table 1 and two small errors in Table 2. In Table 1, the Eron Class III Clinical Criteria should read CrCl <30 mL/min or on dialysis, not CrCl <20 mL/min. In Table 2, Distribution of SOLO patients in modified Eron Classes I–III, the number of outpatients receiving vancomycin (VAN) in Class I should be 111, not 11. The total number of inpatients (Class I–III) was omitted, n = 1143 (59.8%).

Table 1.

Clinical criteria used to define modified Eron Classes I–IV

Eron class Clinical criteria
IV

Bacteremia (positive blood culture); or

Absolute total neutrophils count <500

III

Meeting SIRS criteria

CrCl <30 mL/min or on dialysis

ALT/AST >10-times ULN

Heart rate >90/min, breath rate >20/min, or systolic BP <90 mmHg; or

Cancer

II

Age ≥75 years old

Glucose >11.1 mmol/L

Congestive heart failure at the randomization

30 mL/min < CrCl <60 mL/min

Hepatitis (excluding AST/ALT >10-times ULN)

Peripheral vascular disease

Diabetes mellitus

Fever (temperature >38.0 °C); or

BMI ≥30 kg/m2

I For the patients who didn’t meet Classes II–IV

ALT alanine transaminase, AST aspartate transaminase, BMI body mass index, BP blood pressure, CrCl creatinine clearance, SIRS systemic inflammatory response syndrome, ULN upper limit of normal

Table 2.

Distribution of SOLO patients in modified Eron Classes I–III (mITT population, n = 1959)

Class I Class II Class III Total (Class I–III)
SOLO mITT (n = 1959) 520 (26.5%) 790 (40.3%) 600 (30.6%) 1910
Inpatients, n (%) 301 (57.9%) 431 (54.6%) 411 (68.5%) 1143 (59.8%)
ORI, n 144 224 203 571
VAN, n 157 207 208 572
Outpatients, n (%) 219 (42.1%) 359 (45.4%) 189 (31.5%) 767 (40.2%)
ORI, n 108 182 89 379
VAN, n 111 177 100 388

mITT modified intent-to-treat, ORI oritavancin, VAN vancomycin

Open Access

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Footnotes

The online version of the original article can be found under doi:10.1007/s40121-016-0119-9.

Contributor Information

Daniel H. Deck, Email: Daniel.Deck@THEMEDCO.com

Jennifer M. Jordan, Email: Jennifer.jordan@themedco.com


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