Abstract
Argyrophilic nucleolar organiser regions (AgNORs) in 28 follicular lymphomas and 30 lymph nodes showing reactive follicular hyperplasia were studied to see if they were helpful in distinguishing follicular lymphoma from follicular hyperplasia in paraffin wax tissue sections. Mean nuclear counts were greater in follicular hyperplasia (3.71 v 3.11). This difference was significant but counts overlapped so much that they were of no practical value in distinguishing between both conditions. Higher counts may reflect greater proliferative activity in follicular hyperplasia.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Crocker J., Ayres J., McGovern J. Nucleolar organiser regions in small cell carcinoma of the bronchus. Thorax. 1987 Dec;42(12):972–975. doi: 10.1136/thx.42.12.972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Crocker J., McGovern J. Nucleolar organiser regions in normal, cirrhotic, and carcinomatous livers. J Clin Pathol. 1988 Oct;41(10):1044–1048. doi: 10.1136/jcp.41.10.1044. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Crocker J., Skilbeck N. Nucleolar organiser region associated proteins in cutaneous melanotic lesions: a quantitative study. J Clin Pathol. 1987 Aug;40(8):885–889. doi: 10.1136/jcp.40.8.885. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Egan M. J., Raafat F., Crocker J., Smith K. Nucleolar organiser regions in fibrous proliferations of childhood and infantile fibrosarcoma. J Clin Pathol. 1988 Jan;41(1):31–33. doi: 10.1136/jcp.41.1.31. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Egan M., Ramsden K., Crocker J. Diagnostic significance of mean numbers of nucleolar organizer regions in benign and malignant transitional tumours of nose. Histopathology. 1988 Nov;13(5):579–581. doi: 10.1111/j.1365-2559.1988.tb02085.x. [DOI] [PubMed] [Google Scholar]
- Giri D. D., Nottingham J. F., Lawry J., Dundas S. A., Underwood J. C. Silver-binding nucleolar organizer regions (AgNORs) in benign and malignant breast lesions: correlations with ploidy and growth phase by DNA flow cytometry. J Pathol. 1989 Apr;157(4):307–313. doi: 10.1002/path.1711570407. [DOI] [PubMed] [Google Scholar]
- Hall P. A., Crocker J., Watts A., Stansfeld A. G. A comparison of nucleolar organizer region staining and Ki-67 immunostaining in non-Hodgkin's lymphoma. Histopathology. 1988 Apr;12(4):373–381. doi: 10.1111/j.1365-2559.1988.tb01952.x. [DOI] [PubMed] [Google Scholar]
- Morgan D. W., Crocker J., Watts A., Shenoi P. M. Salivary gland tumours studied by means of the AgNOR technique. Histopathology. 1988 Nov;13(5):553–559. doi: 10.1111/j.1365-2559.1988.tb02079.x. [DOI] [PubMed] [Google Scholar]
- Robertson E. A., Zweig M. H., Van Steirteghem A. C. Evaluating the clinical efficacy of laboratory tests. Am J Clin Pathol. 1983 Jan;79(1):78–86. doi: 10.1093/ajcp/79.1.78. [DOI] [PubMed] [Google Scholar]
- Schwarzacher H. G., Wachtler F. Nucleolus organizer regions and nucleoli. Hum Genet. 1983;63(2):89–99. doi: 10.1007/BF00291525. [DOI] [PubMed] [Google Scholar]
- Smith R., Crocker J. Evaluation of nucleolar organizer region-associated proteins in breast malignancy. Histopathology. 1988 Feb;12(2):113–125. doi: 10.1111/j.1365-2559.1988.tb01923.x. [DOI] [PubMed] [Google Scholar]
- Wagner B. M. New frontiers in neonatal neuropathology. Hum Pathol. 1987 Jan;18(1):1–2. doi: 10.1016/s0046-8177(87)80185-5. [DOI] [PubMed] [Google Scholar]
- Walker R. A. The histopathological evaluation of nucleolar organizer region proteins. Histopathology. 1988 Feb;12(2):221–223. doi: 10.1111/j.1365-2559.1988.tb01932.x. [DOI] [PubMed] [Google Scholar]