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. 1989 Dec;42(12):1296–1297. doi: 10.1136/jcp.42.12.1296

Differentiation between Bernard-Soulier syndrome and immune thrombocytopenia by immunostaining of peripheral blood.

L O Poulsen 1, P Johansen 1, M K Jensen 1, L Freund 1
PMCID: PMC502064  PMID: 2693494

Abstract

Peripheral blood smears from seven patients with Bernard-Soulier syndrome were examined by an immunocytochemical staining procedure using a monoclonal antibody specific for platelet glycoprotein Ib. No platelet staining was observed except for very slight staining of the large sized platelets from one of the patients. Application of the assay to blood smears from 12 patients with immune thrombocytopenia showed that their peripheral platelets stained normally, so the assay can be used to differentiate between immune thrombocytopenia and Bernard-Soulier syndrome and to confirm a diagnosis of the syndrome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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