Abstract
IgD myeloma is a rare disorder with a very poor prognosis. An unusual case is reported where prolonged remission was obtained. Immunohistochemical staining of the bone marrow trephine biopsy specimen proved invaluable in documenting early relapse. It is suggested that immunohistochemistry should be adopted more widely in view of the disparities evident in aspirates and trephines.
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Selected References
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- Hansen O. P., Jessen B., Videbaek A. Prognosis of myelomatosis on treatment with prednisone and cytostatics. Scand J Haematol. 1973;10(4):282–290. doi: 10.1111/j.1600-0609.1973.tb00073.x. [DOI] [PubMed] [Google Scholar]
- Jancelewicz Z., Takatsuki K., Sugai S., Pruzanski W. IgD multiple myeloma. Review of 133 cases. Arch Intern Med. 1975 Jan;135(1):87–93. [PubMed] [Google Scholar]
- Kyle R. A. Long-term survival in multiple myeloma. N Engl J Med. 1983 Feb 10;308(6):314–316. doi: 10.1056/NEJM198302103080604. [DOI] [PubMed] [Google Scholar]
- MacLennan I. C., Chapman C., Dunn J., Kelly K. Combined chemotherapy with ABCM versus melphalan for treatment of myelomatosis. The Medical Research Council Working Party for Leukaemia in Adults. Lancet. 1992 Jan 25;339(8787):200–205. doi: 10.1016/0140-6736(92)90004-m. [DOI] [PubMed] [Google Scholar]
- ROWE D. S., FAHEY J. L. A NEW CLASS OF HUMAN IMMUNOGLOBULINS. I. A UNIQUE MYELOMA PROTEIN. J Exp Med. 1965 Jan 1;121:171–184. doi: 10.1084/jem.121.1.171. [DOI] [PMC free article] [PubMed] [Google Scholar]