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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1994 Aug;47(8):774–775. doi: 10.1136/jcp.47.8.774

Effect of collagenase on nerve fibre teasing.

M Tatke 1, D Doyle 1
PMCID: PMC502161  PMID: 7962641

Abstract

Teased fibre preparations are important in the investigation of peripheral nerve disorders, but can be a rather tedious procedure. A technique is described in which pretreatment of the nerve sample with collagenase before osmication substantially simplifies the actual teasing procedure. The technique also does not alter the morphology or interfere with any further investigations required on teased fibres--for example, fluorescent antibody studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Fleischmajer R., Perlish J. S., Timpl R. Collagen fibrillogenesis in human skin. Ann N Y Acad Sci. 1985;460:246–257. doi: 10.1111/j.1749-6632.1985.tb51172.x. [DOI] [PubMed] [Google Scholar]
  2. Kettle P., Morris T. C. Late relapse in IgD myeloma: value of immunohistochemistry in trephine biopsy specimens. J Clin Pathol. 1994 Aug;47(8):773–774. doi: 10.1136/jcp.47.8.773. [DOI] [PMC free article] [PubMed] [Google Scholar]

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